Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845248 | 0.99 | PLA2G4B (0.40) | PLA2G4BNPC1ALDH1A1KMT2AGGPS1 | |
| SCHEMBL3844865 | 0.92 | PPARA (0.48) | PLA2G4BNPC1ALDH1A1KMT2AGGPS1 | |
| SCHEMBL3839949 | 0.92 | PPARA (0.46) | PLA2G4BNPC1ALDH1A1KMT2AGGPS1 | |
| SCHEMBL3841481 | 0.92 | PPARA (0.51) | NPC1ALDH1A1KMT2AGGPS1PPARG | |
| SCHEMBL3849240 | 0.91 | PPARA (0.48) | PLA2G4BNPC1ALDH1A1KMT2APPARG | |
| SCHEMBL3841370 | 0.89 | PPARA (0.48) | PLA2G4BNPC1ALDH1A1KMT2APPARG | |
| SCHEMBL3842859 | 0.86 | PPARA (0.42) | PPARGPPARA | |
| SCHEMBL3847191 | 0.86 | PPARG (0.42) | PPARGPPARASMPD1 | |
| SCHEMBL3842005 | 0.86 | PPARG (0.42) | PPARGPPARA | |
| SCHEMBL3289722 | 0.85 | PPARA (0.51) | PLA2G4BNPC1ALDH1A1KMT2AGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |