Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849869 | 0.96 | PPARG (0.38) | PPARGPPARACNOT7KDM4EHTT | |
| SCHEMBL3841974 | 0.91 | PPARG (0.38) | PPARGPPARACNOT7MEN1KMT2A | |
| SCHEMBL3845660 | 0.90 | S1PR1 (0.36) | PPARGPPARACNOT7MEN1KMT2A | |
| SCHEMBL3849410 | 0.89 | PPARG (0.40) | PPARGPPARACNOT7KDM4EADORA3 | |
| SCHEMBL3841397 | 0.87 | PPARG (0.32) | PPARGPPARATPSAB1 | |
| SCHEMBL3842931 | 0.87 | PPARA (0.43) | PPARGPPARAADORA3TP53 | |
| SCHEMBL3840290 | 0.87 | PPARG (0.39) | PPARGPPARACNOT7KDM4EHTT | |
| SCHEMBL3843493 | 0.85 | PPARG (0.37) | PPARGPPARAADORA3TP53 | |
| SCHEMBL3285113 | 0.85 | PPARA (0.40) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL3841112 | 0.84 | PPARG (0.39) | PPARGPPARAKDM4EADORA3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |