Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843493 | 0.91 | PPARG (0.37) | PPARGPPARAPPARDS1PR2S1PR4 | |
| SCHEMBL3285913 | 0.91 | TPSAB1 (0.32) | PPARGPPARAPPARDTPSAB1MAOA | |
| SCHEMBL3849869 | 0.90 | PPARG (0.38) | PPARGPPARAPPARDS1PR2S1PR4 | |
| SCHEMBL3840711 | 0.89 | MAOA (0.33) | PPARGPPARAPPARDMAOAMAOB | |
| SCHEMBL3846355 | 0.87 | PPARG (0.37) | PPARGPPARATPSAB1 | |
| SCHEMBL3849410 | 0.86 | PPARG (0.40) | PPARGPPARAPPARDMAOAMAOB | |
| SCHEMBL3284562 | 0.85 | PPARA (0.34) | PPARGPPARA | |
| SCHEMBL3842931 | 0.84 | PPARA (0.43) | PPARGPPARAPPARD | |
| SCHEMBL3844324 | 0.84 | PPARG (0.38) | PPARGPPARAPPARDS1PR2S1PR4 | |
| SCHEMBL3844889 | 0.83 | PPARA (0.42) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |