Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 13/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418848 | 1.00 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL31195718 | 0.98 | S1PR1 (0.43) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL1920012 | 0.98 | S1PR1 (0.43) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL3901604 | 0.95 | S1PR1 (0.41) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL3910037 | 0.92 | NOTUM (0.44) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL3899152 | 0.86 | KIF11 (0.44) | S1PR1S1PR3 | |
| SCHEMBL2235318 | 0.85 | S1PR1 (0.43) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL22074501 | 0.85 | OPRL1 (0.43) | S1PR1S1PR3 | |
| SCHEMBL22504242 | 0.84 | S1PR1 (0.42) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL20863953 | 0.84 | S1PR1 (0.42) | S1PR1S1PR3S1PR4S1PR5ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784839-B | Preparation method of 4-cyclohexyl-3- (trifluoromethyl) benzyl alcohol | 浙江工业大学 | 2024-06-21 | — | — | CN | claimed |
| CN-115784839-A | Preparation method of 4-cyclohexyl-3- (trifluoromethyl) benzyl alcohol | 浙江工业大学 | 2023-03-14 | — | — | CN | claimed |
| CN-113896650-A | Synthesis method of siponimod intermediate | 成都科圣原医药科技有限公司 | 2022-01-07 | — | — | CN | claimed |
| EP-4737450-A1 | HETEROAROMATIC FORMAMIDE COMPOUNDS AND USES THEREOF IN MEDICINE | Longwood Pharmaceuticals (Hangzhou) Co., Ltd (CN) | 2026-05-06 | — | — | EP | disclosed |
| US-12410126-B2 | Process for making Siponimod and intermediate thereof | SYNTHON B.V. (NL) | 2025-09-09 | — | — | US | disclosed |
| CN-119638586-A | Trifluoromethyl cyclohexyl benzyl ether substituted nitrogenous organic acid derivative, preparation method and application thereof | 中国医学科学院药物研究所 | 2025-03-18 | — | — | CN | disclosed |
| WO-2025001956-A1 | HETEROAROMATIC FORMAMIDE COMPOUNDS AND USES THEREOF IN MEDICINE | 远森制药（杭州）有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-115784839-B | Preparation method of 4-cyclohexyl-3- (trifluoromethyl) benzyl alcohol | 浙江工业大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-115784839-B | Preparation method of 4-cyclohexyl-3- (trifluoromethyl) benzyl alcohol | 浙江工业大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-115784839-B | Preparation method of 4-cyclohexyl-3- (trifluoromethyl) benzyl alcohol | 浙江工业大学 | 2024-06-21 | — | — | CN | disclosed |
| US-20230212115-A1 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORME THEREOF | CIPLA LIMITED (IN) | 2023-07-06 | — | — | US | disclosed |
| US-20070203100-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2007-08-30 | — | — | US | disclosed |
| CN-1921863-A | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2007-02-28 | — | — | CN | disclosed |
| EP-1718307-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM, LLC (BM) | 2006-11-08 | — | — | EP | disclosed |
| CN-1787817-A | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2006-06-14 | — | — | CN | disclosed |
| US-7060697-B2 | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2006-06-13 | — | — | US | disclosed |
| EP-1638551-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005082089-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2005-09-09 | — | — | WO | disclosed |
| US-20050014724-A1 | Immunosuppressant compounds and compositions | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2005-01-20 | — | — | US | disclosed |
| WO-2004103309-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212115-A1 | METHODS FOR THE PREPARATION OF SPHINGOSINE 1-PHOSPHATE RECEPTOR MODULATORS AND SOLID FORME THEREOF | S1PR1, S1PR2, S1PR3 | S1PR1 1/4885S1PR3 3/4885S1PR4 4/4885 |
| US-12410126-B2 | Process for making Siponimod and intermediate thereof | S1PR5, SPHK2, S1PR2 | S1PR1 4/4885S1PR3 7/4885S1PR4 5/4885 |
| US-20070203100-A1 | Immunosuppressant Compounds and Compositions | ICOS, EDNRA, NFATC1 | S1PR1 133/4885S1PR3 142/4885S1PR4 211/4885 |
| US-20050014724-A1 | Immunosuppressant compounds and compositions | ICOS, EDNRA, NFATC1 | S1PR1 133/4885S1PR3 142/4885S1PR4 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.