Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.67 |
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | PPARG | P37231 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FABP2 | P12104 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12328025 | 1.00 | ADRB3 (0.67) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL3848024 | 0.95 | ADRB3 (0.73) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL2440421 | 0.88 | PPARA (0.66) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL12953439 | 0.88 | PPARG (0.74) | ADRB3PPARAPPARGPPARDS1PR1 | |
| SCHEMBL4576026 | 0.87 | PPARA (0.54) | ADRB3PPARAPPARGSIGMAR1S1PR1 | |
| SCHEMBL3841460 | 0.86 | PPARA (0.59) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL12953097 | 0.85 | PPARG (0.71) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL16144191 | 0.82 | PPARA (0.52) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL6544080 | 0.82 | PPARA (0.57) | ADRB3PPARAPPARGKDM4EMAPT | |
| SCHEMBL6542915 | 0.82 | PPARA (0.57) | ADRB3PPARAPPARGKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |