Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637870 | 1.00 | CYP1A2 (0.67) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL502837 | 1.00 | CYP1A2 (0.67) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL28971374 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL28971376 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL30301175 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL5597362 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL10706539 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL1984871 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL3128493 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL3128499 | 0.98 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109929822-B | Aspergillus oryzae lipase mutant and application thereof | 浙江工业大学 | 2021-04-06 | — | — | CN | claimed |
| CN-106187678-B | The preparation method of one kind chloro- 1,2- propylene glycol of (R) -3- | 上海科利生物医药有限公司 | 2019-03-08 | — | — | CN | claimed |
| CN-108821962-A | A method of synthesis herbicide clodinafop-propargyl key intermediate | 浙江工业大学 | 2018-11-16 | — | — | CN | claimed |
| CN-106187678-A | A kind of preparation method of (R) 3 chlorine 1,2 propylene glycol | 上海科利生物医药有限公司 | 2016-12-07 | — | — | CN | claimed |
| US-20090326258-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRALIN AND SUBSTITUTED INDANE DERIVATIVES | ZHAN-PLASKET FAN | 2009-12-31 | — | — | US | claimed |
| US-20080096962-A1 | Process for the Preparation of Substituted Tetralin and Substituted Indane Derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-24 | — | — | US | claimed |
| CN-101018766-A | Process for preparing substituted tetralin and substituted indane derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2007-08-15 | — | — | CN | claimed |
| EP-1745016-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRALIN AND SUBSTITUTED INDANE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-24 | — | — | EP | claimed |
| WO-2005105737-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRALIN AND SUBSTITUTED INDANE DERIVATIVES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-11-10 | — | — | WO | claimed |
| US-20050240049-A1 | Process for the preparation of substituted tetralin and substituted indane derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-10-27 | — | — | US | claimed |
| CN-1179937-C | Process for prep. of (R)-and (S)-2-(4-hydroxy-pheneyloxy) propionic acid and/or its alkyl ester mixture | �����ɷ� | 2004-12-15 | — | — | CN | claimed |
| CN-1332147-A | Process for prep. of (R)-and (S)-2-(4-hydroxy-pheneyloxy) propionic acid and/or its alkyl ester mixture | BASF AG (DE) | 2002-01-23 | — | — | CN | claimed |
| EP-0701547-B1 | THE PREPARATION OF MIXTURES OF (R)- AND (S)-2-(4-ALKANOYLPHENOXY)- OR (R)- AND (S)-2-(4-AROYLPHENOXY)PROPIONIC ESTERS | BASF AG (DE) | 1998-07-29 | — | — | EP | claimed |
| CN-1124954-A | Process for preparing -and- (S) -2- (4-alkanoylphenoxy) -or -and- (S) -2- (4-aroylphenoxy) propionate mixture | BASF AG (DE) | 1996-06-19 | — | — | CN | claimed |
| EP-0701547-A1 | THE PREPARATION OF MIXTURES OF (R)- AND (S)-2-(4-ALKANOYLPHENOXY)- OR (R)- AND (S)-2-(4-AROYLPHENOXY)PROPIONIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1996-03-20 | — | — | EP | claimed |
| WO-1994027950-A1 | THE PREPARATION OF MIXTURES OF (R)- AND (S)-2-(4-ALKANOYLPHENOXY)- OR (R)- AND (S)-2-(4-AROYLPHENOXY)PROPIONIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | claimed |
| CN-112812002-B | Preparation method of (R) - (+) -2- (4-hydroxyphenoxy) propionic acid | 锦州三丰科技有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-112812002-A | Preparation method of (R) - (+) -2- (4-hydroxyphenoxy) propionic acid | 锦州三丰科技有限公司 | 2021-05-18 | — | — | CN | disclosed |
| US-5296363-A | Oxidizing 2-phenoxypropionic acid under aerobic conditions in presence of soil inhabiting Streptomycetes bacteria or fungus | BASE AKTIENGESELLSCHAFT (DE) | 1994-03-22 | — | — | US | disclosed |
| US-4760172-A | Process for the preparation of optically active 2-(4-methoxyphenoxy) propionic acid | THE DOW CHEMICAL COMPANY (US) | 1988-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326258-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRALIN AND SUBSTITUTED INDANE DERIVATIVES | TDO2, ITPA, TTI2 | CYP1A2 59/4885GAA 2523/4885CYP2C9 199/4885 |
| US-20080096962-A1 | Process for the Preparation of Substituted Tetralin and Substituted Indane Derivatives | TDO2, ITPA, TTI2 | CYP1A2 59/4885GAA 2523/4885CYP2C9 199/4885 |
| US-20050240049-A1 | Process for the preparation of substituted tetralin and substituted indane derivatives | TDO2, TTI2, ITPA | CYP1A2 54/4885GAA 2579/4885CYP2C9 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.