Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DCK | P27707 | 3/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831482 | 0.80 | GAA (0.49) | MAP4K4POLBGAAGCKPIN1 | |
| SCHEMBL5498019 | 0.79 | MAP4K4 (0.45) | MAP4K4POLBGAADCKGCK | |
| SCHEMBL8611666 | 0.73 | MAP4K4 (0.50) | MAP4K4POLBGAAGCKPIN1 | |
| SCHEMBL3833794 | 0.71 | MAP4K4 (0.39) | MAP4K4POLBGAADCKGCK | |
| SCHEMBL1222332 | 0.71 | ALOX5AP (0.37) | GAAGCKPIN1LRRK2ALOX5AP | |
| SCHEMBL28242322 | 0.70 | GAA (0.51) | MAP4K4POLBGAAGCKPIN1 | |
| SCHEMBL1493266 | 0.70 | MEN1 (0.39) | POLBALOX5APFEN1 | |
| SCHEMBL6804830 | 0.68 | MEN1 (0.44) | GAAMAPK14ALOX5APFEN1 | |
| SCHEMBL7108791 | 0.68 | MAP4K4 (0.52) | MAP4K4POLBGAAGCKPIN1 | |
| SCHEMBL28100319 | 0.67 | MAPK14 (0.49) | MAP4K4POLBGAADCKGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102174-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYNOPHENOXY-PYRIMIDINYLOXY-PHENYL ACRYLATE DERIVATIVES | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008075341-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYNOPHENOXY-PYRIMIDINYLOXY-PHENYL ACRYLATE DERIVATIVES | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2008-06-26 | — | — | WO | disclosed |