Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108791 | 0.76 | MAP4K4 (0.52) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL28100319 | 0.75 | MAPK14 (0.49) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL3848429 | 0.73 | MAP4K4 (0.43) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL28629538 | 0.73 | MAP4K4 (0.44) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL28627153 | 0.73 | MAP4K4 (0.44) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL7173106 | 0.73 | MAP4K4 (0.50) | MAP4K4GAAPOLBPIN1MAPK14 | |
| SCHEMBL24507690 | 0.72 | MAP4K4 (0.56) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL29090763 | 0.72 | MAP4K4 (0.52) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL21484222 | 0.72 | MAP4K4 (0.56) | MAP4K4GAAPOLBPIN1GCK | |
| SCHEMBL7054403 | 0.72 | GAA (0.64) | MAP4K4GAAPOLBPIN1GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726343-A | REACTION OF A BORONIC ACID COMPOUND WITH A METHOXYIMINOACETIC ESTER, INSECTICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-03-10 | — | — | US | claimed |