Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643387 | 1.00 | DDB1 (0.33) | DDB1CRBNITGB3ITGB2ITGB1 | |
| SCHEMBL125144 | 1.00 | DDB1 (0.33) | DDB1CRBNITGB3ITGB2ITGB1 | |
| SCHEMBL17817920 | 0.88 | ITGB3 (0.31) | CRBNITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL17817927 | 0.88 | ITGB3 (0.31) | CRBNITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL17536556 | 0.86 | KDM4E (0.32) | CRBNPOLB | |
| SCHEMBL4777313 | 0.82 | POLB (0.34) | DDB1CRBNPOLBGAALMNA | |
| SCHEMBL27630074 | 0.82 | POLB (0.34) | DDB1CRBNPOLBGAALMNA | |
| SCHEMBL27711372 | 0.82 | POLB (0.34) | DDB1CRBNPOLBGAALMNA | |
| SCHEMBL29144132 | 0.82 | DDB1 (0.33) | DDB1CRBNPOLBGAALMNA | |
| SCHEMBL17817929 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758371-B1 | NEW THIO DERIVATIVES BEARING LACTAMS AS POTENT HDAC INHIBITORS AND THEIR USES AS MEDICAMENTS | SIGMA TAU IND FARMACEUTI (IT) | 2016-06-15 | — | — | EP | claimed |
| EP-1858866-B1 | PYROGLUTAMATE SALTS AND THEIR USE IN THE OPTICAL RESOLUTION OF INTERMEDIATES FOR THE SYNTHESIS OF DEXTROCETIRIZINE AND LEVOCETIRIZINE | UCB FARCHIM SA (CH) | 2009-06-10 | — | — | EP | claimed |
| EP-1259213-B1 | USE OF PYRROLIDINONE CARBOXYLIC ACIDS AND POLYMERS | HENKEL KGAA (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1259213-A1 | USE OF PYRROLIDINONE CARBOXYLIC ACIDS AND POLYMERS | Hans Schwarzkopf GmbH & Co. KG (DE) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064172-A1 | USE OF PYRROLIDINONE CARBOXYLIC ACIDS AND POLYMERS | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2001-09-07 | — | — | WO | disclosed |