SCHEMBL384895

SCHEMBL384895

O=C(O)C(Cc1ccccc1)=C(Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.64
CES2 O00748 1/20 0.64
AKR1B1 P15121 1/20 0.64
CTBP2 P56545 1/20 0.56
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
EPHX2 P34913 1/20 0.50
PAM P19021 2/20 0.48
TSHR P16473 2/20 0.48
ABCC4 O15439 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3881031 1.00 CES1 (0.64) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL384894 1.00 CES1 (0.64) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL304073 0.97 CES1 (0.61) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL304071 0.97 CES1 (0.61) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL9856517 0.89 CES1 (0.52) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL28146029 0.88 CES1 (0.56) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL305659 0.87 CES1 (0.50) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL10193598 0.87 KEAP1 (0.57) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL305657 0.87 CES1 (0.50) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL6046963 0.86 CES1 (0.54) CES1CES2AKR1B1CTBP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671822-A Method for preparing alpha-heteroatom functionalized 2-oxazoline and compound 浙江师范大学 2022-06-28 CN claimed
EP-3156433-B1 COATING COMPOSITIONS INCLUDING A POLYISOCYANATE CHAIN EXTENDED NH FUNCTIONAL PREPOLYMER AXALTA COATING SYSTEMS IP CO (US) 2018-06-27 EP claimed
EP-1791824-B1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO KK (JP) 2009-08-05 EP claimed
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
US-7294680-B2 Method of producing conjugated diene polymers with narrow molecular weight distribution and polymer produced JSR CORPORATION (JP) 2007-11-13 US claimed
US-20040147694-A1 Method of producing conjugated diene polymers with narrow molecular weight distribution and polymer produced JSR CORPORATION 2004-07-29 US claimed
EP-0863165-B1 Method of producing conjugated diene polymers JSR CORP (JP) 2003-06-04 EP claimed
EP-0863165-A1 Method of producing conjugated diene polymers JSR Corporation (JP) 1998-09-09 EP claimed
EP-0266617-B1 MODIFIED POLYPHENYLENE ETHER RESINS HAVING IMPROVED FOAMABILITY AND METHODS OF MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 1992-07-15 EP claimed
EP-0183552-B2 A PHOTOPOLYMERIZABLE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-10-16 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed
EP-0183552-B1 A PHOTOPOLYMERIZABLE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-03-16 EP claimed
EP-3904072-B1 SPECTACLE LENS HOYA LENS THAILAND LTD (TH) 2026-04-15 EP disclosed
US-12435181-B2 Formulations capable of reacting with or removal of molecular oxygen LI SHENSHEN (US) 2025-10-07 US disclosed
US-12337559-B2 Polarizing film, method for molding polarizing film, and method for producing polarizing lens HOYA LENS THAILAND LTD. (TH) 2025-06-24 US disclosed
US-4427820-A STYRENE, MALEIC ACID DERIVATIVE, EMULSION POLYMERIZATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-24 US disclosed
EP-0031997-B1 POLYMERISATION PROCESS FOR PRODUCTION OF POLYMER MICROPARTICLES OF HIGH REFRACTIVE INDEX AND COATING COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-28 EP disclosed
EP-0031997-A1 Polymerisation process for production of polymer microparticles of high refractive index and coating compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-07-15 EP disclosed
US-4240450-A HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS L'OREAL (FR) 1980-12-23 US disclosed