SCHEMBL384977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10107138	1.00	LMNA (0.41)	LMNAKDM4EABL1L3MBTL1MAPT
	SCHEMBL16433611	0.92	KDM4E (0.39)	LMNAKDM4EABL1L3MBTL1MAPT
	SCHEMBL13799816	0.88	KDM4E (0.41)	LMNAKDM4EABL1HRH3SCD
	SCHEMBL10119801	0.88	KDM4E (0.41)	LMNAKDM4EABL1HRH3SCD
	SCHEMBL10107254	0.87	KDM4E (0.41)	LMNAKDM4EABL1MAPTHRH3
	SCHEMBL385376	0.87	KDM4E (0.41)	LMNAKDM4EABL1MAPTHRH3
	SCHEMBL13799813	0.87	KDM4E (0.41)	LMNAKDM4EABL1MAPTHRH3
	SCHEMBL10107103	0.86	HCRTR1 (0.41)	LMNAKDM4EABL1HRH3SCD
	SCHEMBL385891	0.86	HCRTR1 (0.41)	LMNAKDM4EABL1HRH3SCD
	SCHEMBL10107196	0.84	KDM4E (0.39)	LMNAKDM4EABL1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.