⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133019 | 0.86 | SLC6A4 (0.34) | — | |
| SCHEMBL11884347 | 0.84 | — | — | |
| SCHEMBL11850381 | 0.84 | L3MBTL1 (0.30) | — | |
| SCHEMBL4389933 | 0.81 | — | — | |
| SCHEMBL4620512 | 0.80 | — | — | |
| SCHEMBL3391990 | 0.80 | — | — | |
| SCHEMBL10639828 | 0.80 | — | — | |
| SCHEMBL4063062 | 0.80 | EPHX1 (0.32) | — | |
| SCHEMBL1784213 | 0.78 | L3MBTL1 (0.30) | — | |
| SCHEMBL118102 | 0.78 | CYP3A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576125-B2 | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-08-18 | — | — | US | disclosed |
| US-20060088485-A1 | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-04-27 | — | — | US | disclosed |
| WO-2004071481-A1 | MELANOGENESIS INHIBITOR AND SKIN PREPARATION CONTAINING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-26 | — | — | WO | disclosed |
| EP-0180252-A1 | Process of preparing azetidinone compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0070204-A2 | Carboxylic beta-lactam compounds and the preparation thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |