Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713785 | 0.90 | FYN (0.44) | FYNRAD52TDO2NAMPT | |
| SCHEMBL3846791 | 0.88 | MAPK8 (0.45) | FYNRAD52TDO2NAMPT | |
| SCHEMBL3847437 | 0.80 | L3MBTL1 (0.40) | FYNRAD52TDO2 | |
| SCHEMBL3323152 | 0.80 | KLK7 (0.43) | FYN | |
| Hydrochloric Acid SCHEMBL3854393 | 0.79 | FLT3 (0.42) | FYN | |
| SCHEMBL13874137 | 0.78 | FLT3 (0.51) | FYN | |
| Hydrochloric Acid SCHEMBL3846588 | 0.78 | FLT3 (0.56) | — | |
| Hydrochloric Acid SCHEMBL3856609 | 0.78 | FYN (0.47) | FYN | |
| SCHEMBL3853399 | 0.78 | FYN (0.47) | FYNRAD52 | |
| Hydrochloric Acid SCHEMBL3856691 | 0.77 | FLT3 (0.50) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |