Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902953 | 0.87 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29781083 | 0.87 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29524946 | 0.87 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29725642 | 0.86 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL4251782 | 0.86 | NR1H2 (0.54) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL18537881 | 0.84 | NR1H2 (0.53) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL5599682 | 0.82 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL5957852 | 0.82 | NR1H2 (0.51) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL24894603 | 0.81 | NOD2 (0.62) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29827958 | 0.81 | NOD2 (0.62) | NR1H2NR1H3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099741-A2 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | University Of Virginia Patent Foundation (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008064320-A2 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-05-29 | — | — | WO | disclosed |