Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057028 | 0.85 | PKM (0.67) | TSHRSMN1; SMN2PKMMAPK1HTT | |
| SCHEMBL31172608 | 0.85 | PKM (0.61) | TSHRSMN1; SMN2PKMCA12CA2 | |
| SCHEMBL18726107 | 0.84 | TSHR (0.60) | TSHRSMN1; SMN2PKMCYP1A2CYP2C19 | |
| SCHEMBL13680440 | 0.84 | TSHR (0.60) | TSHRSMN1; SMN2PKMCYP1A2CYP2C19 | |
| Water SCHEMBL7908328 | 0.82 | TSHR (0.59) | TSHRSMN1; SMN2PKMCYP1A2CYP2C19 | |
| SCHEMBL8777836 | 0.81 | PKM (0.73) | TSHRSMN1; SMN2PKMCYP1A2CYP2C19 | |
| SCHEMBL6585989 | 0.80 | TSHR (0.66) | TSHRSMN1; SMN2PKMHTTGLA | |
| SCHEMBL11688578 | 0.80 | PKM (0.70) | TSHRPKMCA12CA2CA9 | |
| SCHEMBL11715302 | 0.79 | PKM (0.58) | TSHRSMN1; SMN2PKMMAPK1HTT | |
| SCHEMBL20182618 | 0.78 | POLB (0.53) | TSHRSMN1; SMN2CYP2C19CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582766-B2 | Inhibitors of papilloma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| US-7582766-B2 | Inhibitors of papilloma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-1636200-A2 | INHIBITORS OF PAPILLOMA VIRUS | Boehringer Ingelheim International GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20050014791-A1 | Inhibitors of papilloma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108673-A2 | INHIBITORS OF PAPILLOMA VIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-16 | — | — | WO | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014791-A1 | Inhibitors of papilloma virus | TPD52L2, ZC3HAV1, CCNE2 | TSHR 4256/4885SMN1; SMN2 4778/4885PKM 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.