Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.39 |
| ▸ | CA1 | P00915 | 12/20 | 0.39 |
| ▸ | CA12 | O43570 | 12/20 | 0.39 |
| ▸ | CA9 | Q16790 | 11/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.37 |
| ▸ | CA7 | P43166 | 6/20 | 0.37 |
| ▸ | CA4 | P22748 | 6/20 | 0.37 |
| ▸ | CA6 | P23280 | 5/20 | 0.37 |
| ▸ | CA5A | P35218 | 5/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236090 | 0.74 | CA2 (0.50) | CA2CA1CA12CA9MAPT | |
| SCHEMBL4758944 | 0.66 | CA1 (0.49) | CA2CA1CA12CA9MAPT | |
| SCHEMBL11744639 | 0.66 | NOX1 (0.55) | CA2CA1CA12CA9MAPT | |
| SCHEMBL9673758 | 0.64 | CA2 (0.46) | CA2 | |
| SCHEMBL2591105 | 0.63 | CA2 (0.42) | CA2CA1CA12CA9MAPT | |
| SCHEMBL15202208 | 0.63 | CA2 (0.42) | CA2CA1CA12CA9MAPT | |
| SCHEMBL31236117 | 0.63 | CA1 (0.36) | CA2CA1CA12CA9MAPT | |
| SCHEMBL2710652 | 0.62 | CA2 (0.41) | CA2CA1CA12CA9MAPT | |
| SCHEMBL4020727 | 0.62 | CA2 (0.49) | CA2CA1CA12CA9MAPT | |
| SCHEMBL30210907 | 0.62 | CA2 (0.62) | CA2CA1CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | claimed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | claimed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | claimed |
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |