⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393427 | 0.84 | — | — | |
| SCHEMBL2845442 | 0.81 | — | — | |
| SCHEMBL10031019 | 0.80 | PKM (0.51) | — | |
| SCHEMBL91500 | 0.78 | — | — | |
| SCHEMBL2642121 | 0.77 | — | — | |
| SCHEMBL914923 | 0.76 | — | — | |
| SCHEMBL507355 | 0.76 | — | — | |
| SCHEMBL7250089 | 0.76 | — | — | |
| SCHEMBL7250091 | 0.76 | — | — | |
| SCHEMBL131562 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023330-A1 | QUINAZOLINE DERIVATIVE | 石药集团中奇制药技术（石家庄）有限公司 | 2016-02-18 | — | — | WO | disclosed |
| EP-1888082-B1 | MOTILIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2012-09-12 | — | — | EP | disclosed |
| CN-101203227-B | Ergotrophic lactone compound | PFIZER | 2011-01-12 | — | — | CN | disclosed |
| US-7582611-B2 | Treating disorders of gastric motility; decreasing side effects of erythromycin A | PFIZER INC. (US) | 2009-09-01 | — | — | US | disclosed |
| CN-101203227-A | Ergotrophic lactone compound | PFIZER (US) | 2008-06-18 | — | — | CN | disclosed |
| US-20060270616-A1 | Motilide compounds | PFIZER INC. | 2006-11-30 | — | — | US | disclosed |