Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380271 | 0.93 | TDP1 (0.52) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| SCHEMBL15859 | 0.87 | TDP1 (0.75) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| SCHEMBL2461414 | 0.84 | — | — | |
| SCHEMBL5131831 | 0.84 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| SCHEMBL26967080 | 0.84 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| Ammonia Solution, Strong SCHEMBL7104676 | 0.84 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| SCHEMBL5129514 | 0.84 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| SCHEMBL7184727 | 0.82 | — | — | |
| SCHEMBL14943804 | 0.81 | TDP1 (0.68) | TDP1PAOXCYP2C9CYP2C19DPP7 | |
| SCHEMBL5131976 | 0.81 | TDP1 (0.68) | TDP1PAOXCYP2C9CYP2C19DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793215-A | Modified organopolysiloxane and preparation method and application thereof | 唐山三友硅业有限责任公司 | 2020-10-20 | — | — | CN | claimed |
| CN-106459271-A | Multifunctional acrylic oligomers of branched structure, by polyaddition between multifunctional amines and acrylates | 阿科玛法国公司 | 2017-02-22 | — | — | CN | claimed |
| CN-111793215-B | Modified organopolysiloxane, preparation method and application thereof | 唐山三友硅业有限责任公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-111793215-A | Modified organopolysiloxane and preparation method and application thereof | 唐山三友硅业有限责任公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-106459271-A | Multifunctional acrylic oligomers of branched structure, by polyaddition between multifunctional amines and acrylates | 阿科玛法国公司 | 2017-02-22 | — | — | CN | disclosed |
| US-9346919-B2 | Polysiloxane-polyether copolymers with amino groups and/or quaternary ammonium groups in the polyether moiety and processes for the preparation thereof | EVONIK DEGUSSA GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| WO-2015142689-A1 | SLIP RESISTANT ARTICLE AND THE METHOD FOR PREPARING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-24 | — | — | WO | disclosed |
| US-20150080427-A1 | BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | AUSPEX PHARMACEUTICALS, INC. | 2015-03-19 | — | — | US | disclosed |
| CN-102947362-B | Foam insulation unit | DOW GLOBAL TECHNOLOGIES LLC | 2015-03-18 | — | — | CN | disclosed |
| US-20140303065-A1 | Polysiloxane-polyether copolymers with amino groups and/or quaternary ammonium groups in the polyether moiety and processes for the preparation thereof | EVONIK INDUSTRIES AG (DE) | 2014-10-09 | — | — | US | disclosed |
| CN-102020672-B | Alkoxy silicane functionalized betaine zwitterionic compound and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2013-08-21 | — | — | CN | disclosed |
| CN-102020672-A | Alkoxy silicane functionalized betaine zwitterionic compound and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2011-04-20 | — | — | CN | disclosed |
| US-7582700-B2 | Method for the production of emulsions of highly-viscous organopolysiloxanes | WACKER CHEMIE AG (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-1773920-B1 | METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2008-04-09 | — | — | EP | disclosed |
| US-20080033062-A1 | Method for the Production of Emulsions of Highly-Viscous Organopolysiloxanes | WACKER CHEMIE AG (DE) | 2008-02-07 | — | — | US | disclosed |
| US-7126020-B2 | Reactions rapidly complete or proceeds at low temperature such as room temperature; highly viscous and stable products with Si C-bonded radicals containing basic nitrogen | WACKER CHEMIE AG (DE) | 2006-10-24 | — | — | US | disclosed |
| EP-1541615-B1 | Method for the production of highly viscous organopolysiloxanes | WACKER CHEMIE AG (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20050131243-A1 | Process for preparing highly viscous organopolysiloxanes | WACKER-CHEMIE GMBH (DE) | 2005-06-16 | — | — | US | disclosed |
| EP-1541615-A1 | Method for the production of highly viscous organopolysiloxanes | Wacker-Chemie GmbH (DE) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080427-A1 | BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | SLC18A2, SLC6A2, SLC18A1 | TDP1 1159/4885PAOX 800/4885CYP2C9 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.