⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661071 | 0.70 | — | — | |
| SCHEMBL3675158 | 0.70 | — | — | |
| SCHEMBL14348032 | 0.70 | — | — | |
| SCHEMBL3315282 | 0.67 | — | — | |
| SCHEMBL1766118 | 0.63 | — | — | |
| SCHEMBL456468 | 0.60 | — | — | |
| SCHEMBL2695895 | 0.60 | — | — | |
| SCHEMBL1295855 | 0.60 | — | — | |
| SCHEMBL2731837 | 0.60 | — | — | |
| SCHEMBL14981214 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745283-A | Heterocyclic derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-12 | — | — | CN | claimed |
| CN-113416229-A | Cytotoxic and antimitotic compounds, and methods of use thereof | 酵活有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-104961666-B | 2-mercaptoacetamide pleuromutilin derivatives, and preparation method and medical application thereof | 南通大学 | 2017-04-12 | — | — | CN | claimed |
| CN-104447450-B | Cysteine amide-type pleuromutilin derivative and preparation method and medical usage | 南通大学 | 2016-09-28 | — | — | CN | claimed |
| CN-104961666-A | 2-mercaptoacetamide pleuromutilin derivatives, and preparation method and medical application thereof | UNIV NANTONG | 2015-10-07 | — | — | CN | claimed |
| CN-104447450-A | Cysteine amide type pleuromutilin derivative as well as preparation method and medical application thereof | UNIV NANTONG | 2015-03-25 | — | — | CN | claimed |
| CN-101293888-A | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-10-29 | — | — | CN | claimed |
| CN-1492870-A | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-04-28 | — | — | CN | claimed |
| CN-116745283-A | Heterocyclic derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116568675-A | Cyclic isothiourea derivatives as CXCR4 modulators | 埃尔米乌治疗公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-111138366-B | Pyrazole carbamoyl derivatives, preparation method and application thereof | 天津药物研究院有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115703758-A | Compound used as kinase inhibitor and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-02-17 | — | — | CN | disclosed |
| CN-111138357-B | 2-oxo-1, 2-dihydroquinoline derivative, preparation method and medical application thereof | 天津药物研究院有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-111989311-B | Compound for inhibiting PGE2/EP4 signal transduction, preparation method thereof and application thereof in medicines | 凯复(苏州)生物医药有限公司 | 2022-03-22 | — | — | CN | disclosed |
| WO-1996007421-A2 | AN ANTIULCER MEDICINE COMPRISING A PROTEIN POSSESSING ALL GROWTH FACTOR ACTIVITY AND A PROTON PUMP INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-14 | — | — | WO | disclosed |
| EP-0649655-A1 | Injectable solutions containing anti-ulcer benzimidazoles and amides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-26 | — | — | EP | disclosed |
| WO-1995010519-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1995-04-20 | — | — | WO | disclosed |
| EP-0645140-A1 | Compositions for rectal administration containing benzimidazoles and fatty acid salts | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |
| EP-0642797-A1 | Formulation comprising antibacterial substance and antiulcer substance | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0154906-A2 | 3-Cyclopropylmethyl-1,3,5-triazine-2,4-dione | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |