Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MPI | P34949 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854967 | 1.00 | MAPK1 (0.47) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL13679917 | 1.00 | MAPK1 (0.47) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL3853101 | 0.87 | MAPT (0.53) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL3853099 | 0.87 | MAPT (0.53) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL3859873 | 0.83 | MAPT (0.59) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL3859871 | 0.83 | MAPT (0.59) | MAPK1MAPTALDH1A1GAAMEN1 | |
| Perchlorate SCHEMBL3863336 | 0.82 | MAPT (0.53) | MAPK1MAPTALDH1A1GAAMEN1 | |
| Perchlorate SCHEMBL3863334 | 0.82 | MAPT (0.53) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL3853825 | 0.81 | MAPT (0.53) | MAPK1MAPTALDH1A1GAAMEN1 | |
| SCHEMBL3853822 | 0.81 | MAPT (0.53) | MAPK1MAPTALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-20090044348-A1 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-02-19 | — | — | US | disclosed |
| EP-2011787-A1 | Dying composition comprising an azomethin-type compound with a pyrazolinone moiety | L'Oreal (FR) | 2009-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090044348-A1 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | KRT18, KMO, TMPO | MAPK1 814/4885MAPT 308/4885ALDH1A1 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.