Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | TOP1 | P11387 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL9849701 | 1.00 | EP300 (0.47) | EP300TSHRPPARGTERTPTPN1 | |
| Formic Acid SCHEMBL5026964 | 0.98 | TSHR (0.50) | EP300TSHRPPARGTERTPTPN1 | |
| Formic Acid SCHEMBL11035923 | 0.98 | TSHR (0.50) | EP300TSHRPPARGTERTPTPN1 | |
| Formic Acid SCHEMBL4249498 | 0.93 | TSHR (0.46) | EP300TSHRPPARGTERTPTPN1 | |
| Formic Acid SCHEMBL4256859 | 0.93 | TSHR (0.46) | EP300TSHRPPARGTERTPTPN1 | |
| SCHEMBL128509 | 0.93 | — | — | |
| SCHEMBL1276035 | 0.91 | EP300 (0.56) | EP300TSHRPPARGTERTPTPN1 | |
| SCHEMBL159834 | 0.91 | EP300 (0.56) | EP300TSHRPPARGTERTPTPN1 | |
| SCHEMBL241496 | 0.91 | EP300 (0.56) | EP300TSHRPPARGTERTPTPN1 | |
| SCHEMBL1275165 | 0.91 | EP300 (0.56) | EP300TSHRPPARGTERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582678-B2 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | D-PHARM LIMITED (IL) | 2009-09-01 | — | — | US | disclosed |
| EP-1419129-B1 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | DPHARM LTD (IL) | 2008-12-03 | — | — | EP | disclosed |
| EP-1419129-A4 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | DPHARM LTD (IL) | 2006-05-10 | — | — | EP | disclosed |
| US-20040235949-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | D-PHARM LIMITED (IL) | 2004-11-25 | — | — | US | disclosed |
| EP-1419129-A2 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | D-Pharm Limited (IL) | 2004-05-19 | — | — | EP | disclosed |
| US-6518311-B2 | Analgesics | D-PHARM LTD. (IL) | 2003-02-11 | — | — | US | disclosed |
| WO-2003000173-A2 | USE OF BRANCHED-CHAIN FATTY ACIDS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN | D-PHARM LIMITED (IL) | 2003-01-03 | — | — | WO | disclosed |
| US-20020042445-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | D-PHARM LTD. (IL) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235949-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | OPRL1, ELOVL5, ELOVL1 | EP300 2610/4885TSHR 3438/4885PPARG 51/4885 |
| US-20020042445-A1 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain | OPRL1, ELOVL5, ELOVL1 | EP300 2610/4885TSHR 3438/4885PPARG 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.