Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11143842 | 0.98 | KDM4E (0.46) | RAD52GFERKDM4EMAPTGAA | |
| SCHEMBL9499966 | 0.87 | GAA (0.47) | RAD52GFERKDM4EMAPTGAA | |
| SCHEMBL11142464 | 0.84 | MAPT (0.49) | KDM4EMAPTGAAPOLBTSHR | |
| SCHEMBL15933187 | 0.83 | TSHR (0.42) | KDM4EMAPTGAAPOLBTSHR | |
| SCHEMBL6574341 | 0.83 | HDAC4 (0.38) | KDM4EMAPTGAATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11140483 | 0.83 | GAA (0.51) | KDM4EMAPTGAAPOLBTSHR | |
| SCHEMBL7807418 | 0.83 | MAPT (0.41) | RAD52GFERMAPTGAAPOLB | |
| SCHEMBL7484048 | 0.82 | TSHR (0.49) | RAD52GFERKDM4EMAPTGAA | |
| SCHEMBL7484042 | 0.81 | GBA1 (0.37) | RAD52GFERKDM4EGAATSHR | |
| SCHEMBL11822323 | 0.81 | MAPT (0.58) | KDM4EMAPTGAAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | claimed |
| EP-3079651-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'Oréal (FR) | 2016-10-19 | — | — | EP | claimed |
| WO-2015086676-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2015-06-18 | — | — | WO | claimed |
| US-5180396-A | Process for dyeing keratinous fibres with oxidation dyes combined with indole derivatives and dyeing composition employed | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| US-5180397-A | Hair dyes | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| US-4985955-A | INTENSE COLORATIONS IN RELATIVELY SHORT TIMES | L'OREAL (FR) | 1991-01-22 | — | — | US | claimed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| EP-3079651-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'Oréal (FR) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015086676-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015086676-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2015-06-18 | — | — | WO | disclosed |
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| EP-0507448-A2 | Oxidative hair dyeing process with catalytic pretreatment | Bristol-Myers Squibb Company (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5100436-A | Transition metal complex of 2,2*-dipyridine or 1,10-phenanthroline deposited on hair, reduced time for coloring | CLAIROL INCORPORATED (US) | 1992-03-31 | — | — | US | disclosed |
| US-5032138-A | Chlorites as oxidants in hair coloring | CLAIROL INCORPORATED (US) | 1991-07-16 | — | — | US | disclosed |
| US-4985955-A | INTENSE COLORATIONS IN RELATIVELY SHORT TIMES | L'OREAL (FR) | 1991-01-22 | — | — | US | disclosed |
| EP-0399746-A1 | Use of chlorites as oxidants in hair coloring | Bristol-Myers Squibb Company (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4420637-A | HAIR DYES, OXIDATION | L'OREAL (FR) | 1983-12-13 | — | — | US | disclosed |
| US-4305717-A | P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES | L'OREAL (FR) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | KRT18, VIM, SORD | RAD52 630/4885GFER 313/4885KDM4E 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.