Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29251289 | 0.75 | GRM5 (0.52) | GRM5PTGDR2MMEECE1IKBKB | |
| Fluoride SCHEMBL31286347 | 0.73 | GRM5 (0.50) | GRM5PTGDR2MMEECE1IKBKB | |
| Charcoal, Activated SCHEMBL31286314 | 0.73 | GRM5 (0.50) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL28124359 | 0.72 | GRM5 (0.42) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL16457122 | 0.69 | GRM5 (0.43) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL28016125 | 0.69 | GRM5 (0.43) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL849221 | 0.67 | GRM5 (0.42) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL301745 | 0.67 | GRM5 (0.42) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL8767077 | 0.67 | GRM5 (0.46) | GRM5PTGDR2MMEECE1IKBKB | |
| SCHEMBL28311795 | 0.67 | GRM5 (0.42) | GRM5PTGDR2MMEECE1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723140-B1 | PROCESS FOR THE PREPARATION OF TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-11-04 | — | — | EP | claimed |