SCHEMBL3856369

SCHEMBL3856369

Cc1c(N=C2C=CC(=O)C(Cl)=C2)c(=O)n(-c2ccccc2)n1C

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.78
▸ MEN1 O00255 6/20 0.78
▸ KMT2A Q03164 6/20 0.78
▸ MAPK1 P28482 5/20 0.78
▸ KDM4E B2RXH2 3/20 0.78
▸ THRB P10828 2/20 0.78
▸ ATM Q13315 1/20 0.78
▸ ALDH1A1 P00352 10/20 0.69
▸ GAA P10253 8/20 0.69
▸ MPI P34949 3/20 0.69
▸ BLM P54132 1/20 0.69
▸ HTT P42858 3/20 0.64
▸ LMNA P02545 3/20 0.64
▸ POLB P06746 3/20 0.61
▸ TDP1 Q9NUW8 2/20 0.61
▸ G6PD P11413 1/20 0.61
▸ RECQL P46063 1/20 0.61
▸ MITF O75030 1/20 0.60
▸ NSD2 O96028 1/20 0.60
▸ OPRK1 P41145 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3856367 1.00 MAPT (0.78) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL13680312 1.00 MAPT (0.78) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL3854531 0.88 MAPT (1.00) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL3854527 0.88 MAPT (1.00) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL13680051 0.88 MAPT (1.00) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL5508785 0.86 MAPT (0.76) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL20122064 0.85 MAPT (0.78) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL3854924 0.84 MAPT (0.76) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL3861573 0.84 MAPT (0.76) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL3854926 0.84 MAPT (0.76) MAPTMEN1KMT2AMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3928070-B2 — — 2007-06-13 — — JP claimed
EP-0767809-B1 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING & MFG (US) 2004-01-21 — — EP claimed
EP-0767809-A2 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-04-16 — — EP claimed
US-5596025-A POLYSILOXANE CURABLE BY HYDROSILATION REACTION, COLOR CHANGE ON CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-21 — — US claimed
US-5583178-A ADDITION POLYMER AND A CURE INDICATING DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-10 — — US claimed
WO-1996000745-A2 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-11 — — WO claimed
US-9670330-B2 Method and dye mixtures for marking shape memory polymers, and shape memory polymer articles with switchable readability BAM Bundesanstalt fuer Materialforschung und—Pruefung (DE) 2017-06-06 — — US disclosed
US-20150119238-A1 METHOD AND DYE MIXTURES FOR MARKING SHAPE MEMORY POLYMERS, AND SHAPE MEMORY POLYMER ARTICLES WITH SWITCHABLE READABILITY BAM BUNDESANSTALT FUER MATERIALFORSCHUNG UND - PRUEFUNG (DE) 2015-04-30 — — US disclosed
EP-2771392-A2 METHOD AND DYE MIXTURES FOR MARKING SHAPE MEMORY POLYMERS, AND SHAPE MEMORY POLYMER ARTICLES WITH SWITCHABLE READABILITY BAM Bundesanstalt für Materialforschung und -prüfung (DE) 2014-09-03 — — EP disclosed
WO-2013060831-A2 METHOD AND DYE MIXTURES FOR MARKING SHAPE MEMORY POLYMERS, AND SHAPE MEMORY POLYMER ARTICLES WITH SWITCHABLE READABILITY BAM Bundesanstalt für Materialforschung und -prüfung (DE) 2013-05-02 — — WO disclosed
US-7582123-B2 Coloring composition comprising at least one azomethine compound with a pyrazolinone unit L'OREAL S.A. (FR) 2009-09-01 — — US disclosed
US-7582123-B2 Coloring composition comprising at least one azomethine compound with a pyrazolinone unit L'OREAL S.A. (FR) 2009-09-01 — — US disclosed
US-7582123-B2 Coloring composition comprising at least one azomethine compound with a pyrazolinone unit L'OREAL S.A. (FR) 2009-09-01 — — US disclosed
EP-0767809-B1 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING & MFG (US) 2004-01-21 — — EP disclosed
EP-0768860-B1 DENTAL IMPRESSION MATERIAL WITH CURE-INDICATING DYE MINNESOTA MINING & MFG (US) 2003-04-23 — — EP disclosed
WO-2003008009-A1 LIGHT EMITTING MARKERS FOR USE WITH SUBSTRATES SCIMED LIFE SYSTEMS, INC. (US) 2003-01-30 — — WO disclosed
US-20030015284-A1 SATURATING WITH MIXTURE OF COPOLYMERS OF DIMETHYLSILOXANE AND POLYSTYRENE; DRAINAGE, DRYING, COATING, REMOVAL AND POLISHING; FLOWER SHAPE, TEXTURE, SIZE, AND COLOR IS RETAINED; WEAR RESISTANCE, DURABILITY BOSTON SCIENTIFIC SCIMED, INC. 2003-01-23 — — US disclosed
US-5596025-A POLYSILOXANE CURABLE BY HYDROSILATION REACTION, COLOR CHANGE ON CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-21 — — US disclosed
US-5583178-A ADDITION POLYMER AND A CURE INDICATING DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-10 — — US disclosed
WO-1996000745-A2 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-11 — — WO disclosed
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