Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | THRB | P10828 | 2/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.69 |
| ▸ | GAA | P10253 | 6/20 | 0.69 |
| ▸ | MPI | P34949 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680051 | 0.88 | MAPT (1.00) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3854527 | 0.88 | MAPT (1.00) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3854531 | 0.88 | MAPT (1.00) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL13680312 | 0.85 | MAPT (0.78) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3856369 | 0.85 | MAPT (0.78) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3856367 | 0.85 | MAPT (0.78) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3861573 | 0.84 | MAPT (0.76) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3854926 | 0.84 | MAPT (0.76) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3854924 | 0.84 | MAPT (0.76) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3864724 | 0.82 | ALDH1A1 (1.00) | MAPTMAPK1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9964552-B2 | Mass spectrometric identification and/or quantitation of catecholamines using aminopyrazoles | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2018-05-08 | — | — | US | disclosed |