SCHEMBL3856902

SCHEMBL3856902

NC1(Cc2ccccc2)CCCN1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443388 0.78
SCHEMBL443387 0.78
SCHEMBL5907267 0.77 NOS2 (0.37)
SCHEMBL1320294 0.77 NPC1 (0.43)
SCHEMBL1317731 0.77
SCHEMBL16738412 0.76
SCHEMBL20958614 0.76
SCHEMBL693699 0.76
SCHEMBL15312902 0.76
SCHEMBL29046163 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009124167-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK & CO., INC. (US) 2009-10-08 WO disclosed