Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SQLE | Q14534 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982384 | 0.80 | TSHR (0.38) | TSHRSQLEALDH1A1KMT2AMEN1 | |
| SCHEMBL31346264 | 0.76 | TSHR (0.35) | TSHRSQLEALDH1A1KMT2A | |
| SCHEMBL31346266 | 0.75 | CES2 (0.36) | TSHRALDH1A1KMT2AMEN1ALOX15 | |
| SCHEMBL31346265 | 0.73 | CES2 (0.38) | TSHRALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL7610384 | 0.72 | — | — | |
| SCHEMBL437402 | 0.69 | — | — | |
| SCHEMBL20966 | 0.68 | — | — | |
| SCHEMBL8388178 | 0.68 | KMT2A (0.36) | TSHRSQLEALDH1A1KMT2AMEN1 | |
| SCHEMBL9792633 | 0.67 | TSHR (0.50) | TSHRSQLEALDH1A1KMT2AMEN1 | |
| SCHEMBL7768795 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858914-A4 | PEPTIDE NETWORKS | UNIV QUEENSLAND (AU) | 2009-01-14 | — | — | EP | disclosed |
| EP-1858914-A1 | PEPTIDE NETWORKS | The University of Queensland (AU) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006089364-A1 | PEPTIDE NETWORKS | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-08-31 | — | — | WO | disclosed |