SCHEMBL3857558

SCHEMBL3857558

C=CCC(C#N)CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL28052045 0.92 ALDH1A1 (0.31)
SCHEMBL9765930 0.84
SCHEMBL21557607 0.84
SCHEMBL3146002 0.82
SCHEMBL6687143 0.80
SCHEMBL11331193 0.80 ALDH1A1 (0.42)
SCHEMBL11070712 0.78 TSHR (0.37)
SCHEMBL23530156 0.77
SCHEMBL5879379 0.77 TSHR (0.38)
Bicarbonate SCHEMBL11768566 0.75 GRIK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4404167-A AMINO NITRILE INHIBITORS ROZENFELD IOSIF L 1983-09-13 US claimed
US-20240026184-A1 FLUOROPOLYETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2024-01-25 US disclosed
CN-104725381-A Growth factor receptor inhibitor and application thereof NANJING SANHOME PHARMACEUTICAL CO LTD 2015-06-24 CN disclosed
CN-1880400-B Adhesive SUMITOMO CHEMICAL CO 2010-04-21 CN disclosed
US-7585570-B2 A curable adhesive comprising acrylic ester polymers, a polysilsesquioxane or polysilicate, and a disisocyanate crosslinking agent; liquid crystal displays; glass substrates; films; durability; antipeeling agents; haze-free, nonblistering; antifoam agents; resistant to repeated cycles of heating/cooling SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-08 US disclosed
CN-1880400-A Adhesive SUMITOMO CHEMICAL CO (JP) 2006-12-20 CN disclosed
US-20060252863-A1 A curable adhesive comprising acrylic ester polymers, a polysilsesquioxane or polysilicate, and a disisocyanate crosslinking agent; liquid crystal displays; glass substrates; films; durability; antipeeling agents; haze-free, nonblistering; antifoam agents; resistant to repeated cycles of heating/cooling SUMITOMO CHEMICHAL COMPANY, LIMITED 2006-11-09 US disclosed
US-7129308-B2 Functionalized silicon compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2006-10-31 US disclosed
US-7129307-B2 Functionalized silicon compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2006-10-31 US disclosed
US-7125947-B2 Functionalized silicon compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2006-10-24 US disclosed
US-20010021506-A1 Functionalized silicon compounds and methods for their synthesis and use AFFYMETRIX, INC. 2001-09-13 US disclosed
US-20010014453-A1 Functionalized silicon compounds and methods for their synthesis and use AFFYMETRIX, INC. 2001-08-16 US disclosed
WO-2000021967-A1 FUNCTIONALIZED SILICON COMPOUNDS, THEIR SYNTHESIS AND USE AFFYMETRIX, INC. (US) 2000-04-20 WO disclosed
US-5939574-A REATION OF DIALKYLACETONITRILES WITH VINYLSILOXANES FOR TREATMENT OF TEXTILES AND FABRICS WITCO CORPORATION (US) 1999-08-17 US disclosed
US-5939574-A REATION OF DIALKYLACETONITRILES WITH VINYLSILOXANES FOR TREATMENT OF TEXTILES AND FABRICS WITCO CORPORATION (US) 1999-08-17 US disclosed
EP-0924166-A1 THERMOPLASTIC-COATED AMMONIUM POLYPHOSPHATE AND PROCESS FOR THE PREPARATION THEREOF CHISSO CORPORATION (JP) 1999-06-23 EP disclosed
US-4404167-A AMINO NITRILE INHIBITORS ROZENFELD IOSIF L 1983-09-13 US disclosed
EP-0030528-B1 PROCESS FOR THE INTRODUCTION OF ALKYL, ARALKYL OR CYCLOALKYL GROUPS ONTO A FUNCTIONAL GROUP-SUBSTITUTED CARBON CHAIN SANOFI S.A. (FR) 1983-06-22 EP disclosed
US-4377533-A PROPYLATION OF NITRILES SANOFI (FR) 1983-03-22 US disclosed
EP-0030528-A1 Process for the introduction of alkyl, aralkyl or cycloalkyl groups onto a functional group-substituted carbon chain SANOFI S.A. (FR) 1981-06-17 EP disclosed