SCHEMBL385785

SCHEMBL385785

[C]#CCCC(C)CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386397 0.84
SCHEMBL2119263 0.82 LMNA (0.35)
SCHEMBL386044 0.81
SCHEMBL2119101 0.77 ACE2 (0.36)
SCHEMBL5157636 0.76
SCHEMBL8390731 0.74
SCHEMBL9831947 0.74
SCHEMBL138030 0.73
SCHEMBL276462 0.72
SCHEMBL29012400 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074757-B The manufacturing method of trifluoromethyl alkylthio chemical combination object 组合化学工业株式会社 2019-05-03 CN disclosed
EP-2444401-B1 NOVEL IMIDAZOPYRIDINE COMPOUND ONO PHARMACEUTICAL CO (JP) 2014-09-03 EP disclosed
US-8569504-B2 Imidazopyridine compound ONO PHARMACEUTICAL CO., LTD. (JP) 2013-10-29 US disclosed
EP-2444401-A1 NOVEL IMIDAZOPYRIDINE COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2012-04-25 EP disclosed
US-20120094944-A1 NOVEL IMIDAZOPYRIDINE COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-19 US disclosed
US-8101650-B2 Method for treating a immunology-related disease DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-01-24 US disclosed
US-8067396-B2 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2011-11-29 US disclosed
EP-2152668-A1 ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPOD Sumitomo Chemical Company, Limited (JP) 2010-02-17 EP disclosed
US-20100035842-A1 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2010-02-11 US disclosed
US-20100011656-A1 USE OF RYLENES AS MARKERS FOR LIQUIDS BASF SE (DE) 2010-01-21 US disclosed
US-6063181-A 1,7-disubstituted perylene-3,4,9, 10-tetracarboxylic acids, their dianhydrides and diimides of said acids BASF AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
US-5965611-A TREATING CHRONIC PERIPHERAL ARTERIAL OCCLUSION BY ADMINISTERING EMULSION COMPRISING ISOCARBACYCLIN, VEGETABLE OIL, PHOSPHOLIPID, AND WATER TEIGIN LIMITED (JP) 1999-10-12 US disclosed
EP-0634171-B1 PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS TEIJIN LTD (JP) 1999-05-06 EP disclosed
US-5656663-A THERAPY FOR SKIN ULCERS TEIJIN LIMITED (JP) 1997-08-12 US disclosed
EP-0761225-A1 PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL CIRCULATION DISORDER TEIJIN LIMITED (JP) 1997-03-12 EP disclosed
US-5610182-A ADMINISTERING AN ISOCARBACYCLIN OF SPECIFIC STRUCTURE IN THE FORM OF A FAT EMULSION TEIJIN, LIMITED (JP) 1997-03-11 US disclosed
US-5530027-A PROSTAGLANDINS AND/OR ITS OPTICAL ISOMER FOR SKIN DISORDERS TEIJIN LIMITED (JP) 1996-06-25 US disclosed
EP-0638312-A1 DERMATOLOGIC PREPARATION COMPOSITION CONTAINING ISOCARBACYCLIN AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1995-02-15 EP disclosed
EP-0634172-A1 DERMATOLOGIC PREPARATION COMPOSITION CONTAINING PROSTACYCLIN AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1995-01-18 EP disclosed
EP-0634171-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS TEIJIN LIMITED (JP) 1995-01-18 EP disclosed