⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15411495 | 0.74 | — | — | |
| SCHEMBL21611711 | 0.72 | — | — | |
| SCHEMBL3097311 | 0.70 | — | — | |
| SCHEMBL8379435 | 0.70 | — | — | |
| SCHEMBL2239766 | 0.67 | RNASEH1 (0.38) | — | |
| SCHEMBL3847119 | 0.67 | RNASEH1 (0.39) | — | |
| SCHEMBL20734016 | 0.67 | — | — | |
| SCHEMBL2239780 | 0.59 | MEN1 (0.39) | — | |
| SCHEMBL785147 | 0.59 | — | — | |
| SCHEMBL338264 | 0.59 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507496-B | Immunogenic compounds comprising HIV GP41 peptide coupled to CRM197 carrier protein | 伊纳维尔瓦克斯公司 | 2018-08-03 | — | — | CN | disclosed |
| US-7482425-B2 | Compositions for lipid matrix-assisted chemical ligation | AMYLIN PHARMACEUTICALS, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1107979-B1 | LIPID MATRIX-ASSISTED CHEMICAL LIGATION AND SYNTHESIS OF MEMBRANE POLYPEPTIDES | GRYPHON THERAPEUTICS INC (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20030018169-A1 | Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides | AMYLIN PHARMACEUTICALS, INC. | 2003-01-23 | — | — | US | disclosed |
| US-6451543-B1 | PREFOLDED MEMBRANE POLYPEPTIDE EMBEDDED WITHIN A LIPID MATRIX VIA STEPWISE CHEMOSELECTIVE CHEMICAL LIGATION OF UNPROTECTED PEPTIDE SEGMENTS, WHERE AT LEAST ONE PEPTIDE SEGMENT IS EMBEDDED IN A LIPID MATRIX. | GRYPHON SCIENCES | 2002-09-17 | — | — | US | disclosed |