Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL385804

NC(Cc1ccccc1)C(=O)O.NC(Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 1.00
PTGS1 P23219 2/20 1.00
ALPI P09923 1/20 1.00
PKM P14618 1/20 1.00
XIAP P98170 1/20 1.00
SLC1A3 P43003 2/20 0.69
SLC1A2 P43004 2/20 0.69
SLC1A1 P43005 2/20 0.69
SLC15A1 P46059 1/20 0.63
CYP1A2 P05177 1/20 0.61
LTA4H P09960 1/20 0.59
GRIA2 P42262 1/20 0.59
KDM4E B2RXH2 1/20 0.58
USP2 O75604 1/20 0.58
EGFR P00533 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
ALOX15 P16050 1/20 0.58
HTR2A P28223 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL15671104 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL16398196 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL1449124 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL16398197 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL8119 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23159186 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL43671 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL8118 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
D-Phenylalanine SCHEMBL837632 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL1331985 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730969-A Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2023-09-12 CN claimed
CN-115046932-A Chiral molecular sensor based on metal nanosphere trimer and identification method 西北工业大学 2022-09-13 CN claimed
WO-2019216675-A1 EPITOPE OF REGULATORY T CELL SURFACE ANTIGEN AND ANTIBODY SPECIFICALLY BINDING THERETO 주식회사 굳티셀 (KR) 2019-11-14 WO claimed
CN-101781242-A Method for preparing phthaloylamino acid UNIV SHAANXI SCIENCE & TECH 2010-07-21 CN claimed
CN-101781325-A Gallium salicylaldehyde amino acid Schiff base quaternary coordination compound, preparation method and application thereof UNIV BEIJING NORMAL 2010-07-21 CN claimed
CN-116730969-B Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2024-04-19 CN disclosed
WO-2024020635-A1 EXTRACELLULAR MATRIX HYDROGELS THE UNIVERSITY OF NEWCASTLE (AU) 2024-02-01 WO disclosed
CN-116730969-A Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2023-09-12 CN disclosed
US-20230152235-A1 IMPROVED BIOMOLECULE DETECTION USING SURFACE-ENHANCED RAMAN SPECTROSCOPY NOSTICS B.V. (NL) 2023-05-18 US disclosed
CN-112543752-B Linker, antibody conjugate drug containing linker and use of linker 中国人民解放军军事科学院军事医学研究院 2023-04-18 CN disclosed
CN-114062531-A Rheumatoid arthritis early synovial fluid diagnostic kit and application thereof 山东第一医科大学(山东省医学科学院) 2022-02-18 CN disclosed
US-20210061861-A1 D-PEPTIDIC COMPOUNDS FOR VEGF REFLEXION PHARMACEUTICALS, INC. 2021-03-04 US disclosed
CN-1058486-C Separating method for unequal-quantity antipode of phenylalanine UNIV WUHAN (CN) 2000-11-15 CN disclosed
CN-1271250-A Polyamine treatment of neurological disorders MICHAEL A MURPHY (US) 2000-10-25 CN disclosed
EP-1017275-A1 POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS Murphy, Michael A. (US) 2000-07-12 EP disclosed
CN-1235164-A Peptide for vaccine of schistosomiasis UNIV BEIJING MEDICAL (CN) 1999-11-17 CN disclosed
US-5906996-A Tetramine treatment of neurological disorders MURPHY MICHAEL A (US) 1999-05-25 US disclosed
CN-1211567-A Separating method for unequal-quantity antipode of phenylalanine UNIV WUHAN (CN) 1999-03-24 CN disclosed
WO-1999008519-A1 POLYAMINE TREATMENT OF NEUROLOGICAL DISORDERS MURPHY MICHAEL A (US) 1999-02-25 WO disclosed
US-4745210-A AMIDATION OF PHENYLALANINE WITH ANHYDRIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061861-A1 D-PEPTIDIC COMPOUNDS FOR VEGF VEGFA, KDR, FLT1 SLC7A5 758/4885PTGS1 4034/4885ALPI 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.