Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.56 |
| ▸ | CA4 | P22748 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240958 | 0.90 | GLA (1.00) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL1104929 | 0.87 | GLA (0.76) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL1104935 | 0.86 | GLA (0.67) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL11149402 | 0.85 | GLA (0.81) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL385112 | 0.83 | GLA (0.63) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL11501433 | 0.82 | GLA (0.77) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL1094715 | 0.80 | GLA (1.00) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL1827383 | 0.78 | GLA (0.69) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL1093778 | 0.78 | MAOB (0.72) | GLAMEN1KMT2AMAOBCA12 | |
| SCHEMBL8834661 | 0.78 | GLA (0.69) | GLAMEN1KMT2AMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240060949-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | FUNDACION AZTI/AZTI FUNDAZIOA (ES) | 2024-02-22 | — | — | US | claimed |
| EP-4271830-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | Fundacion Azti/Azti Fundazioa (ES) | 2023-11-08 | — | — | EP | claimed |
| WO-2022144095-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | FUNDACION AZTI/AZTI FUNDAZIOA (ES) | 2022-07-07 | — | — | WO | claimed |
| EP-1140888-B1 | OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY | VERTEX PHARMA SAN DIEGO LLC (US) | 2003-05-14 | — | — | EP | claimed |
| US-6420130-B1 | CHEMICAL COMPOUND FOR USE IN THE DETECTION OF PREFERENTIAL ENZYMATIC POLYPEPTIDE | AURORA BIOSCIENCES CORPORATION | 2002-07-16 | — | — | US | claimed |
| EP-4379062-A1 | BIOSYSTEM FOR PESTICIDE DETECTION | Fundación AZTI - AZTI Fundazioa (ES) | 2024-06-05 | — | — | EP | disclosed |
| US-20240175069-A1 | BIOSYSTEM FOR PESTICIDE DETECTION | Fundación AZTI – AZTI Fundazioa (ES) | 2024-05-30 | — | — | US | disclosed |
| US-20240060949-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | FUNDACION AZTI/AZTI FUNDAZIOA (ES) | 2024-02-22 | — | — | US | disclosed |
| EP-4271830-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | Fundacion Azti/Azti Fundazioa (ES) | 2023-11-08 | — | — | EP | disclosed |
| US-20230167482-A1 | FUNCTIONAL CYTOCHROME P450 IN VITRO ASSAY | PHARMGENETIX GMBH (AT) | 2023-06-01 | — | — | US | disclosed |
| EP-4045675-A1 | FUNCTIONAL CYTOCHROME P450 IN VITRO ASSAY | Pharmgenetix GmbH (AT) | 2022-08-24 | — | — | EP | disclosed |
| WO-2022144095-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | FUNDACION AZTI/AZTI FUNDAZIOA (ES) | 2022-07-07 | — | — | WO | disclosed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | disclosed |
| US-20100105095-A1 | Optical Molecular Sensors for Cytochrome P450 Activity | Life Technologies Corporation (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100105095-A1 | Optical Molecular Sensors for Cytochrome P450 Activity | Life Technologies Corporation (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100099728-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-04-22 | — | — | US | disclosed |
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | INVITROGEN CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | INVITROGEN CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| US-20070072256-A1 | OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY | INVITROGEN CORPORATION | 2007-03-29 | — | — | US | disclosed |
| US-20070072256-A1 | OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY | INVITROGEN CORPORATION | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105095-A1 | Optical Molecular Sensors for Cytochrome P450 Activity | CYP2J2, CYP1A2, CYP2B6 | GLA 3166/4885MEN1 4855/4885KMT2A 2421/4885 |
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | CYP2J2, CYP1A2, CYP2B6 | GLA 3166/4885MEN1 4855/4885KMT2A 2421/4885 |
| US-20100099728-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV3, TRPV1, TRPC3 | GLA 2665/4885MEN1 2591/4885KMT2A 4265/4885 |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV3, TRPV1, TRPC3 | GLA 2665/4885MEN1 2591/4885KMT2A 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.