Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRS | Q13332 | 6/20 | 0.78 |
| ▸ | GABRP | O00591 | 3/20 | 0.78 |
| ▸ | GABRD | O14764 | 3/20 | 0.78 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.78 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.78 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.78 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.78 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.78 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.78 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.78 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.78 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.78 |
| ▸ | GABRE | P78334 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.78 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.78 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.78 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.78 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.78 |
| ▸ | FBP1 | P09467 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Scutellarein SCHEMBL29004586 | 0.88 | KMT2A (1.00) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL142093 | 0.88 | KMT2A (1.00) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL29692708 | 0.88 | KMT2A (1.00) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL15241295 | 0.87 | KMT2A (0.97) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL28016997 | 0.87 | KMT2A (0.97) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL28230300 | 0.87 | KMT2A (0.97) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL15090395 | 0.87 | KMT2A (0.97) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| Scutellarein SCHEMBL1900314 | 0.87 | KMT2A (0.97) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8250407 | 0.85 | ABCB1 (0.94) | PTPRSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17258312 | 0.85 | PTPRS (0.78) | PTPRSGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108283634-A | Chrysin and its derivative are preparing the purposes in preventing and treating fatty liver medicament | 东北师范大学 | 2018-07-17 | — | — | CN | disclosed |
| EP-1556031-A4 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES INC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1556031-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | Jenken Bioscience, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037193-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES, INC. (US) | 2004-05-06 | — | — | WO | disclosed |