SCHEMBL3860754

SCHEMBL3860754

O=[N+]([O-])C=Cc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
VCP P55072 3/20 1.00
FBP1 P09467 13/20 0.48
HSP90AA1 P07900 1/20 0.47
EGFR P00533 2/20 0.39
RXRA P19793 1/20 0.38
ABL1 P00519 1/20 0.35
ABL2 P42684 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3860750 1.00 VCP (1.00) VCPFBP1HSP90AA1EGFRRXRA
SCHEMBL16785480 0.76 VCP (0.61) VCPFBP1HSP90AA1EGFRABL1
SCHEMBL29483993 0.76 VCP (0.61) VCPFBP1HSP90AA1EGFRABL1
SCHEMBL19996157 0.76 VCP (0.61) VCPFBP1HSP90AA1EGFRABL1
SCHEMBL19996158 0.76 VCP (0.61) VCPFBP1HSP90AA1EGFRABL1
SCHEMBL18106709 0.76 VCP (0.61) VCPFBP1HSP90AA1EGFRABL1
SCHEMBL19995994 0.73 HSP90AA1 (0.60) VCPFBP1HSP90AA1RXRA
SCHEMBL19995993 0.73 HSP90AA1 (0.60) VCPFBP1HSP90AA1RXRA
SCHEMBL20177575 0.73 VCP (0.57) VCPFBP1HSP90AA1EGFRABL1
SCHEMBL19995980 0.71 HSP90AA1 (0.56) VCPFBP1HSP90AA1EGFRABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271178-A Pentafluoro-beta-nitrostyrene-hexamethylbenzene eutectic and preparation method and application thereof 贵州大学 2024-07-02 CN claimed
US-7132219-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2006-11-07 US claimed
EP-1397260-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2006-03-08 EP claimed
EP-1397260-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2004-03-17 EP claimed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US claimed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US claimed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US claimed
WO-2002062593-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2002-08-15 WO claimed
CN-118271178-A Pentafluoro-beta-nitrostyrene-hexamethylbenzene eutectic and preparation method and application thereof 贵州大学 2024-07-02 CN disclosed
CN-118271178-A Pentafluoro-beta-nitrostyrene-hexamethylbenzene eutectic and preparation method and application thereof 贵州大学 2024-07-02 CN disclosed
CN-118271178-A Pentafluoro-beta-nitrostyrene-hexamethylbenzene eutectic and preparation method and application thereof 贵州大学 2024-07-02 CN disclosed
EP-1493061-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2009-01-07 EP disclosed
US-7132219-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2006-11-07 US disclosed
EP-1493061-A2 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2005-01-05 EP disclosed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US disclosed
WO-2003087233-A2 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-10-23 WO disclosed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US disclosed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US disclosed