SCHEMBL3861217

SCHEMBL3861217

O=C1CCC(=O)c2c1c(I)c(I)c1c2C2(OC1=O)c1ccc(O)cc1Oc1cc(O)ccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.61
ALOX12 P18054 2/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP2C9 P11712 1/20 0.61
ALOX15 P16050 1/20 0.61
BRCA1 P38398 1/20 0.61
HSD17B10 Q99714 1/20 0.61
FTO Q9C0B1 9/20 0.51
MEN1 O00255 2/20 0.51
RECQL P46063 2/20 0.51
BLM P54132 2/20 0.51
KMT2A Q03164 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
MAPT P10636 2/20 0.51
SMAD3 P84022 2/20 0.51
CYP2C19 P33261 1/20 0.51
HTT P42858 1/20 0.51
PRMT1 Q99873 1/20 0.51
ACE2 Q9BYF1 1/20 0.51
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486832 0.86 HPGD (0.64) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL4304748 0.85 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL1263259 0.85 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL212438 0.80 FTO (0.60) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL16432229 0.78 HPGD (0.58) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL6389146 0.77 HPGD (0.54) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL2360878 0.77 FTO (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL342454 0.77 FTO (0.59) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL12496351 0.77 FTO (0.59) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL29355403 0.77 FTO (0.59) HPGDALOX12ALDH1A1CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7413678-B1 Electrically switchable polymer-dispersed liquid crystal materials SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2008-08-19 US claimed
US-7077984-B1 Electrically switchable polymer-dispersed liquid crystal materials SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2006-07-18 US claimed
US-6878494-B2 Switchable volume hologram materials and devices SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2005-04-12 US claimed
US-6821457-B1 PHOTOPOLYMERIZABLE PENTAACRYLATE, CHAIN EXTENDER, INITIATORS, AND CROSSLINKING AGENT; SINGLE STEP, FAST RECORDING OF VOLUME HOLOGRAMS; TRANSMISSION GRATINGS SCIENCE APPLICATIONS INTERNATIONAL CORPORATION 2004-11-23 US claimed
US-20040089842-A1 Switchable volume hologram materials and devices LEIDOS, INC. 2004-05-13 US claimed
US-7583423-B2 Switchable polymer-dispersed liquid crystal optical elements SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2009-09-01 US disclosed
US-7420733-B1 Electrically switchable polymer-dispersed liquid crystal materials including switchable optical couplers and reconfigurable optical interconnects SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2008-09-02 US disclosed
US-7416818-B2 Switchable volume hologram materials and devices SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2008-08-26 US disclosed
US-7413678-B1 Electrically switchable polymer-dispersed liquid crystal materials SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2008-08-19 US disclosed
US-7312906-B2 Switchable polymer-dispersed liquid crystal optical elements SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2007-12-25 US disclosed
US-7265882-B2 Switchable polymer-dispersed liquid crystal optical elements SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2007-09-04 US disclosed
US-7265903-B2 Switchable polymer-dispersed liquid crystal optical elements SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2007-09-04 US disclosed
WO-2000028369-A9 HEAD MOUNTED APPARATUS FOR VIEWING AN IMAGE DIGILENS INC (US) 2000-10-19 WO disclosed
US-6115152-A Holographic illumination system DIGILENS, INC. (US) 2000-09-05 US disclosed
WO-2000041029-A1 SWITCHABLE OPTICAL FILTER EMPLOYING HOLOGRAPHIC OPTICAL ELEMENTS AND IMAGE GENERATING SYSTEM INCORPORATING THE OPTICAL FILTER DIGILENS, INC. (US) 2000-07-13 WO disclosed
WO-2000028369-A2 HEAD MOUNTED APPARATUS FOR VIEWING AN IMAGE DIGILENS, INC. (US) 2000-05-18 WO disclosed
WO-2000016136-A1 HOLOGRAPHIC ILLUMINATION SYSTEM AND HOLOGRAPHIC PROJECTION SYSTEM DIGILENS, INC. (US) 2000-03-23 WO disclosed
WO-2000003274-A1 SWITCHABLE HOLOGRAPHIC OPTICAL SYSTEM DIGILENS, INC. (US) 2000-01-20 WO disclosed
US-5942157-A Switchable volume hologram materials and devices SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 1999-08-24 US disclosed
US-5698343-A Laser wavelength detection and energy dosimetry badge THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-12-16 US disclosed