Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592422 | 0.79 | SHBG (0.50) | SHBGLMNAGPBAR1CYP1A2CYP3A4 | |
| SCHEMBL6284974 | 0.79 | SHBG (0.43) | SHBGLMNAGPBAR1CYP1A2CYP3A4 | |
| SCHEMBL20008783 | 0.78 | SHBG (0.42) | SHBGLMNAGPBAR1CYP1A2CYP3A4 | |
| SCHEMBL3856204 | 0.74 | SHBG (0.41) | SHBGLMNAGPBAR1CYP1A2CYP3A4 | |
| SCHEMBL12883266 | 0.72 | SHBG (0.46) | SHBGLMNAGPBAR1CYP1A2CYP3A4 | |
| SCHEMBL3857214 | 0.72 | CYP3A4 (0.41) | LMNACYP3A4CYP2C19KMT2ACYP19A1 | |
| SCHEMBL15104107 | 0.72 | NR1H4 (0.36) | GPBAR1CYP1A2 | |
| SCHEMBL3857138 | 0.69 | — | — | |
| SCHEMBL3857642 | 0.69 | SHBG (0.31) | SHBG | |
| SCHEMBL20327079 | 0.68 | SHBG (0.59) | SHBGLMNAGPBAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029510-B1 | PATCHOULI ODORANT | FIRMENICH & CIE (CH) | 2013-07-17 | — | — | EP | claimed |
| EP-2029510-B1 | PATCHOULI ODORANT | FIRMENICH & CIE (CH) | 2013-07-17 | — | — | EP | disclosed |
| US-7592492-B2 | Contains perhydro-4-ethyl-8,8a-dimethyl-1-naphthalenol | FIRMENICH SA (CH) | 2009-09-22 | — | — | US | disclosed |
| US-20090130043-A1 | Contains perhydro-4-ethyl-8,8a-dimethyl-1-naphthalenol | FIRMENICH SA, PPON | 2009-05-21 | — | — | US | disclosed |
| EP-2029510-A1 | PATCHOULI ODORANT | Firmenich SA (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007135582-A1 | PATCHOULI ODORANT | FIRMENICH SA (CH) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130043-A1 | Contains perhydro-4-ethyl-8,8a-dimethyl-1-naphthalenol | CYP8B1, CPT1A, HPGD | SHBG 2206/4885LMNA 2338/4885GPBAR1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.