Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.66 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.66 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466744 | 1.00 | GRIK1 (0.66) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL8044187 | 1.00 | GRIK1 (0.66) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL6917703 | 1.00 | GRIK1 (0.66) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL5514956 | 1.00 | GRIK1 (0.66) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| Propylene Glycol SCHEMBL30275310 | 0.95 | GRIK1 (0.60) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL28652152 | 0.92 | SLC1A2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| Glycerin SCHEMBL636012 | 0.92 | GRIK1 (0.57) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL577908 | 0.90 | GRIK1 (0.78) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL1197864 | 0.90 | GRIK1 (0.78) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL6898445 | 0.90 | GRIK1 (0.78) | GRIK1GRIK2SLC1A2SLC1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579375-B2 | Branched carboxylic acid compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-7579375-B2 | Branched carboxylic acid compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-7579375-B2 | Branched carboxylic acid compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20070167522-A1 | Branched carboxylic acid compound and use thereof | ONO PHARMACEUTICAL CO LTD | 2007-07-19 | — | — | US | disclosed |
| US-20070167522-A1 | Branched carboxylic acid compound and use thereof | ONO PHARMACEUTICAL CO LTD | 2007-07-19 | — | — | US | disclosed |
| US-20070167522-A1 | Branched carboxylic acid compound and use thereof | ONO PHARMACEUTICAL CO LTD | 2007-07-19 | — | — | US | disclosed |
| EP-1650182-A1 | BRANCHED CARBOXYLIC ACID COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167522-A1 | Branched carboxylic acid compound and use thereof | BDNF, CA1, BACE1 | GRIK1 230/4885GRIK2 514/4885SLC1A2 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.