Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22558937 | 0.87 | TLR7 (0.68) | TLR7TLR8NUDT1GAATSHR | |
| SCHEMBL3866782 | 0.85 | TLR7 (0.43) | TLR7TLR8DPP4TSHR | |
| SCHEMBL1490883 | 0.84 | TLR7 (0.37) | TLR7DPP4 | |
| SCHEMBL6722232 | 0.84 | TLR7 (0.50) | TLR7TLR8NUDT1NPSR1MEN1 | |
| SCHEMBL2368651 | 0.84 | TLR7 (0.43) | TLR7TLR8NUDT1GAAMEN1 | |
| SCHEMBL3862459 | 0.83 | TLR7 (0.51) | TLR7TLR8GAA | |
| SCHEMBL1490828 | 0.83 | TLR7 (0.45) | TLR7TLR8NUDT1DPP4 | |
| SCHEMBL2370036 | 0.83 | TLR7 (0.53) | TLR7TLR8NUDT1 | |
| SCHEMBL3867066 | 0.83 | TLR7 (0.43) | TLR7TLR8NUDT1NPSR1MEN1 | |
| SCHEMBL3863639 | 0.82 | TLR7 (0.44) | TLR7TLR8NUDT1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7597720-B2 | Oxidizing hair colourant compositions | THE PROCTER & GAMBLE COMPANY (US) | 2009-10-06 | — | — | US | claimed |
| US-20090119852-A1 | Oxidizing Hair Colourant Compositions | WELLA OPERATIONS US, LLC | 2009-05-14 | — | — | US | claimed |
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7091214-B2 | Aryl substituted Imidazoquinolines | 3M INNOVATIVE PROPERTIES CO. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20060111387-A1 | ARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY | 2006-05-25 | — | — | US | disclosed |
| EP-1590348-A1 | ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20040147543-A1 | Aryl substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-07-29 | — | — | US | disclosed |
| WO-2004058759-A1 | ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090119852-A1 | Oxidizing Hair Colourant Compositions | TET1, TET2, TET3 | TLR7 3449/4885TLR8 2799/4885NUDT1 364/4885 |
| US-20040147543-A1 | Aryl substituted imidazoquinolines | IL2, IFNG, IRF3 | TLR7 68/4885TLR8 220/4885NUDT1 648/4885 |
| US-20060111387-A1 | ARYL SUBSTITUTED IMIDAZOQUINOLINES | IL2, IFNG, IRF3 | TLR7 68/4885TLR8 220/4885NUDT1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.