Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.33 |
| ▸ | DHFR | P00374 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210757 | 0.83 | CRHR1 (0.55) | CRHR1TAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL3863541 | 0.78 | CRHR1 (0.51) | CRHR1TAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL3868967 | 0.72 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3206517 | 0.70 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL2056027 | 0.69 | CRHR1 (0.81) | CRHR1SMN1; SMN2 | |
| SCHEMBL3207756 | 0.68 | CRHR1 (0.48) | CRHR1SMN1; SMN2 | |
| SCHEMBL2056029 | 0.68 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL3217975 | 0.68 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL3199789 | 0.68 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3214026 | 0.66 | CRHR1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088861-A2 | BENZIMIDAZOLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008051533-A2 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |