Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857390 | 1.00 | PTGS2 (0.33) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3855955 | 1.00 | PTGS2 (0.33) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3857122 | 0.83 | ALOX5AP (0.31) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3856101 | 0.83 | ALOX5AP (0.31) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3865658 | 0.83 | ALOX5AP (0.31) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3259181 | 0.80 | PTGS2 (0.45) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| Aspirin SCHEMBL3259184 | 0.75 | KDM4E (0.56) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3855130 | 0.73 | PTGS2 (0.34) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3855936 | 0.73 | PTGS2 (0.34) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3860926 | 0.73 | PTGS2 (0.34) | PTGS2KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1843661-A4 | COMPOSITIONS COMPRISING O-ACETYLSALICYL DERIVATIVES OF AMINOCARBOHYDRATES AND AMINO ACIDS | YU RUEY J (US) | 2009-01-14 | — | — | EP | claimed |
| EP-1843661-A2 | COMPOSITIONS COMPRISING O-ACETYLSALICYL DERIVATIVES OF AMINOCARBOHYDRATES AND AMINO ACIDS | Yu, Ruey J., Dr. (US) | 2007-10-17 | — | — | EP | claimed |
| US-20060166901-A1 | Compositions comprising O-acetylsalicyl derivatives of aminocarbohydrates and amino acids | YU RUEY J | 2006-07-27 | — | — | US | claimed |
| WO-2006074114-A2 | COMPOSITIONS COMPRISING O-ACETYLSALICYL DERIVATIVES OF AMINOCARBOHYDRATES AND AMINO ACIDS | YU RUEY J (US) | 2006-07-13 | — | — | WO | claimed |
| EP-1843661-A4 | COMPOSITIONS COMPRISING O-ACETYLSALICYL DERIVATIVES OF AMINOCARBOHYDRATES AND AMINO ACIDS | YU RUEY J (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1843661-A2 | COMPOSITIONS COMPRISING O-ACETYLSALICYL DERIVATIVES OF AMINOCARBOHYDRATES AND AMINO ACIDS | Yu, Ruey J., Dr. (US) | 2007-10-17 | — | — | EP | disclosed |
| US-20060166901-A1 | Compositions comprising O-acetylsalicyl derivatives of aminocarbohydrates and amino acids | YU RUEY J | 2006-07-27 | — | — | US | disclosed |
| WO-2006074114-A2 | COMPOSITIONS COMPRISING O-ACETYLSALICYL DERIVATIVES OF AMINOCARBOHYDRATES AND AMINO ACIDS | YU RUEY J (US) | 2006-07-13 | — | — | WO | disclosed |