SCHEMBL3863451

SCHEMBL3863451

CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(Cc1c[nH]cn1)C(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 18/20 0.46
BACE2 Q9Y5Z0 2/20 0.44
CTSD P07339 1/20 0.43
CTSB P07858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7838077 1.00 BACE1 (0.46) BACE1BACE2CTSDCTSB
SCHEMBL7838083 1.00 BACE1 (0.46) BACE1BACE2CTSDCTSB
SCHEMBL3863461 1.00 BACE1 (0.46) BACE1BACE2CTSDCTSB
SCHEMBL28101251 0.97 BACE1 (0.42) BACE1BACE2CTSD
SCHEMBL30873786 0.94 BACE1 (0.48) BACE1BACE2CTSD
SCHEMBL31471617 0.94 BACE1 (0.45) BACE1BACE2CTSD
SCHEMBL29936688 0.93 NPY1R (0.43)
SCHEMBL29937027 0.93 NPY1R (0.43)
SCHEMBL30032557 0.92 CTSB (0.44) BACE1BACE2CTSB
SCHEMBL31420013 0.91 BACE1 (0.45) BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040259795-A1 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2004-12-23 US claimed
CN-1322214-A Induction of avidin and of Antibioticpeptide Using LAIT/sCD 14-protein GEMMA BIOTECHNOLOGY LTD (CA) 2001-11-14 CN claimed
EP-1080111-B1 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD (CA) 2012-07-25 EP disclosed
EP-1080111-B1 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD (CA) 2012-07-25 EP disclosed
US-7592310-B2 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2009-09-22 US disclosed
US-7592310-B2 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2009-09-22 US disclosed
US-20040259795-A1 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2004-12-23 US disclosed
US-20040259795-A1 Induction of antibiotic proteins and peptides by LAIT/sCD14-protein GEMMA BIOTECHNOLOGY LTD. (CA) 2004-12-23 US disclosed
CN-1322214-A Induction of avidin and of Antibioticpeptide Using LAIT/sCD 14-protein GEMMA BIOTECHNOLOGY LTD (CA) 2001-11-14 CN disclosed
CN-1322214-A Induction of avidin and of Antibioticpeptide Using LAIT/sCD 14-protein GEMMA BIOTECHNOLOGY LTD (CA) 2001-11-14 CN disclosed
EP-1080111-A2 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN Gemma Biotechnology Ltd. (CA) 2001-03-07 EP disclosed
EP-1080111-A2 THE INDUCTION OF ANTIOBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN Gemma Biotechnology Ltd. (CA) 2001-03-07 EP disclosed
WO-1999061468-A3 THE INDUCTION OF ANTIBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD (CA) 2000-04-06 WO disclosed
WO-1999061468-A2 THE INDUCTION OF ANTIBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD. (CA) 1999-12-02 WO disclosed
WO-1999061468-A2 THE INDUCTION OF ANTIBIOTIC PEPTIDES BY LAIT (SCD14) PROTEIN GEMMA BIOTECHNOLOGY LTD. (CA) 1999-12-02 WO disclosed