⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618632 | 1.00 | — | — | |
| SCHEMBL28977853 | 0.73 | — | — | |
| SCHEMBL334131 | 0.73 | — | — | |
| SCHEMBL25955 | 0.73 | — | — | |
| SCHEMBL24132373 | 0.72 | PAX8 (0.30) | — | |
| SCHEMBL19406700 | 0.71 | — | — | |
| SCHEMBL4564185 | 0.71 | — | — | |
| SCHEMBL13752279 | 0.71 | — | — | |
| SCHEMBL31220879 | 0.71 | — | — | |
| SCHEMBL23740957 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100580087-C | Conjugation of peptides | NOVO NORDISK HEALTHCARE AG | 2010-01-13 | — | — | CN | claimed |
| US-20090253166-A1 | Conjugation of Peptides | NOVO NORDISK A/S (DK) | 2009-10-08 | — | — | US | claimed |
| US-20090105134-A1 | C-Terminally Pegylated Growth Hormones | NOVO NORDISK A/S (DK) | 2009-04-23 | — | — | US | claimed |
| JP-2008531482-A | — | — | 2008-08-14 | — | — | JP | claimed |
| EP-1850878-A2 | C-TERMINALLY PEGYLATED GROWTH HORMONES | NOVO NORDISK A/S (DK) | 2007-11-07 | — | — | EP | claimed |
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | claimed |
| US-20070111926-A1 | Conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-17 | — | — | US | claimed |
| CN-1863920-A | Conjugation of peptides | NOVO NORDISK AS (DK) | 2006-11-15 | — | — | CN | claimed |
| WO-2006084888-A2 | C-TERMINALLY PEGYLATED GROWTH HORMONES | NOVO NORDISK A/S (DK) | 2006-08-17 | — | — | WO | claimed |
| EP-1673464-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-28 | — | — | EP | claimed |
| WO-2005035553-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-04-21 | — | — | WO | claimed |
| CN-100580087-C | Conjugation of peptides | NOVO NORDISK HEALTHCARE AG | 2010-01-13 | — | — | CN | disclosed |
| US-20090253166-A1 | Conjugation of Peptides | NOVO NORDISK A/S (DK) | 2009-10-08 | — | — | US | disclosed |
| US-7524813-B2 | Selectively conjugated peptides and methods of making the same | NOVO NORDISK HEALTH CARE AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20090105134-A1 | C-Terminally Pegylated Growth Hormones | NOVO NORDISK A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| WO-2005035553-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-04-21 | — | — | WO | disclosed |
| US-6291674-B2 | REACTING GLYOXAL DERIVATIVE AND AMINOIMIDATE DERIVATIVE TO FORM 3-ALKOXY/ARYLOXY-5-(ALKYL/ARYL)PYRAZINE-2-CARBOXAMIDE; REACTING WITH ALKALI METAL HYPOHALITE TO FORM 3-ALKOXY/ARYLOXY-5-(ALKYL/ARYL)PYRAZINE-2-AMINE | LONZA AG (CH) | 2001-09-18 | — | — | US | disclosed |
| US-20010012894-A1 | Process for preparing alkoxypyrazine derivatives | FUCHS RUDOLF (CH) | 2001-08-09 | — | — | US | disclosed |
| US-6235905-B1 | REACTING A GLYOXAL DERIVATIVE WITH A AMINOACETIMIDATE | LONZA AG (CH) | 2001-05-22 | — | — | US | disclosed |
| US-6066736-A | Process for preparing alkoxypyrazine derivatives | LONZA AG (CH) | 2000-05-23 | — | — | US | disclosed |