Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874782 | 0.82 | KDR (0.42) | F10MAPTKDR | |
| SCHEMBL3862452 | 0.77 | F10 (0.89) | F10 | |
| SCHEMBL3864977 | 0.73 | F10 (0.73) | F10 | |
| SCHEMBL3865235 | 0.71 | F10 (0.72) | F10 | |
| SCHEMBL3866366 | 0.71 | F10 (0.88) | F10MAPT | |
| SCHEMBL3866754 | 0.69 | F10 (0.89) | F10 | |
| SCHEMBL3871409 | 0.67 | F10 (0.71) | F10 | |
| SCHEMBL1678771 | 0.65 | F10 (0.88) | F10 | |
| SCHEMBL3864129 | 0.64 | F10 (0.59) | F10MAPT | |
| SCHEMBL3864251 | 0.64 | F10 (0.88) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566789-B2 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2009-07-28 | — | — | US | claimed |