Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.76 |
| ▸ | PRKCA | P17252 | 5/20 | 0.76 |
| ▸ | BCR | P11274 | 5/20 | 0.76 |
| ▸ | EGFR | P00533 | 3/20 | 0.76 |
| ▸ | SRC | P12931 | 2/20 | 0.76 |
| ▸ | PLK1 | P53350 | 1/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.70 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.62 |
| ▸ | CDK4 | P11802 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | PRKACG | P22612 | 1/20 | 0.57 |
| ▸ | PRKACB | P22694 | 1/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977 | 0.86 | ABL1 (1.00) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL4735604 | 0.86 | PLK1 (1.00) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL8246547 | 0.85 | ABL1 (0.58) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL28983303 | 0.83 | ABL1 (0.71) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL2009 | 0.83 | ABL1 (0.74) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL4734426 | 0.83 | PLK1 (0.80) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL29364396 | 0.83 | ABL1 (0.69) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL1550 | 0.83 | ABL1 (0.69) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL3861941 | 0.83 | ABL1 (0.69) | ABL1PRKCABCREGFRSRC | |
| SCHEMBL6262145 | 0.82 | ABL1 (1.00) | ABL1PRKCABCREGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595323-B2 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof | IL YANG PHARM. CO., LTD. (KR) | 2009-09-29 | — | — | US | disclosed |
| US-7595323-B2 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof | IL YANG PHARM. CO., LTD. (KR) | 2009-09-29 | — | — | US | disclosed |
| US-20040248918-A1 | Anticancer agents | IL YANG PHARM. CO., LTD. | 2004-12-09 | — | — | US | disclosed |
| WO-2004099186-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL YANG PHARM CO., LTD. (KR) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004099187-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL YANG PHARM. CO. LTD. (KR) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248918-A1 | Anticancer agents | BRDT, CHIA, RNASE1 | ABL1 1106/4885PRKCA 2433/4885BCR 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.