Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21478008 | 0.98 | EPHX1 (0.50) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL8222217 | 0.98 | EPHX1 (0.50) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL21337579 | 0.98 | EPHX1 (0.50) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL22047087 | 0.95 | EPHX1 (0.54) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL20354600 | 0.95 | EPHX1 (0.54) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL19836583 | 0.95 | EPHX1 (0.54) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL17071850 | 0.95 | EPHX1 (0.54) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL21089422 | 0.95 | EPHX1 (0.54) | EPHX1LMNAACE2OPRM1ADH1B | |
| SCHEMBL7026506 | 0.91 | EPHX1 (0.46) | EPHX1LMNAACE2OPRM1ALDH1A1 | |
| SCHEMBL21985348 | 0.88 | EPHX1 (0.64) | EPHX1LMNAACE2OPRM1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090326038-A1 | Method for treating a immunology-related disease | SANKYO COMPANY, LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326038-A1 | Method for treating a immunology-related disease | C3AR1, HRH3, HRH2 | EPHX1 941/4885LMNA 3060/4885ACE2 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.