Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462325 | 0.84 | TSHR (0.47) | TSHRMAPK1IDO1CYP1A2CYP2C19 | |
| SCHEMBL3018147 | 0.81 | ALDH1A1 (0.49) | MAPK1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3027815 | 0.78 | MAPT (0.47) | TSHRMAPK1IDO1CYP3A4MEN1 | |
| SCHEMBL2810593 | 0.77 | CA1 (0.40) | CYP1A2CYP2C19CYP3A4KMT2ACYP2D6 | |
| SCHEMBL302713 | 0.75 | MAPT (0.49) | TSHRMAPK1IDO1CYP2C19CYP3A4 | |
| SCHEMBL9268405 | 0.73 | SMN1; SMN2 (0.50) | TSHRMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9417634 | 0.73 | SMN1; SMN2 (0.50) | TSHRMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1047227 | 0.72 | IDO1 (0.60) | MAPK1IDO1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL155790 | 0.72 | IDO1 (0.60) | MAPK1IDO1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2097653 | 0.71 | IDO1 (0.65) | MAPK1IDO1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595424-B2 | Method for producing aromatic amines or aliphatic amino alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-29 | — | — | US | claimed |