Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.65 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.65 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080927 | 0.79 | SMARCA2 (1.00) | SMARCA2SMARCA4LRRK2BRD4NR1I2 | |
| SCHEMBL16968461 | 0.77 | SMARCA2 (0.68) | SMARCA2SMARCA4BRD4GRM2PDK2 | |
| SCHEMBL38650887 | 0.77 | SMARCA2 (0.46) | SMARCA2SMARCA4LRRK2GRM2MAP4K4 | |
| Hydrochloric Acid SCHEMBL30557201 | 0.76 | SMARCA2 (0.67) | SMARCA2SMARCA4BRD4GRM2PDK2 | |
| SCHEMBL25215159 | 0.74 | SMARCA2 (0.61) | SMARCA2SMARCA4LRRK2BRD4NR1I2 | |
| SCHEMBL12138433 | 0.72 | SMARCA2 (0.43) | SMARCA2SMARCA4LRRK2BRD4GRM2 | |
| SCHEMBL38650985 | 0.71 | SMARCA2 (0.45) | SMARCA2SMARCA4LRRK2BRD4GRM2 | |
| SCHEMBL10544187 | 0.68 | SMARCA2 (0.60) | SMARCA2SMARCA4LRRK2BRD4GRM2 | |
| SCHEMBL30549505 | 0.68 | SMARCA2 (0.56) | SMARCA2SMARCA4BRD4GRM2PDK2 | |
| SCHEMBL25599942 | 0.68 | SMARCA2 (0.56) | SMARCA2SMARCA4NR1I2PBRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010963-A | Polycyclic SMARCA2 inhibitor and application thereof | 上海和誉生物医药科技有限公司 | 2026-05-12 | — | — | CN | disclosed |