Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38653272 | 0.89 | ESR2 (0.41) | ESR2NR1H2MAPK1MAPTKDM4E | |
| SCHEMBL30199220 | 0.84 | ESR2 (0.63) | ESR2NR1H2MAPK1ADORA1MAPT | |
| SCHEMBL38653711 | 0.83 | ESR2 (0.52) | ESR2NR1H2MAPK1ADORA1MAPT | |
| SCHEMBL38653323 | 0.82 | ESR2 (0.49) | ESR2NR1H2MAPK1ADORA1MAPT | |
| SCHEMBL29586570 | 0.82 | ESR2 (0.51) | ESR2NR1H2MAPK1ADORA1MAPT | |
| SCHEMBL21326124 | 0.82 | ESR2 (0.51) | ESR2NR1H2MAPK1ADORA1MAPT | |
| SCHEMBL21326079 | 0.79 | NR1H2 (0.69) | ESR2NR1H2MAPK1MAPTDDB1 | |
| SCHEMBL21326100 | 0.79 | ESR2 (0.70) | ESR2NR1H2MAPK1MAPTDDB1 | |
| SCHEMBL29587366 | 0.79 | ESR2 (0.70) | ESR2NR1H2MAPK1MAPTDDB1 | |
| SCHEMBL29586905 | 0.79 | NR1H2 (0.69) | ESR2NR1H2MAPK1MAPTDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099404-A1 | SULFONYLUREA DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | QUBIT PHARMACEUTICALS (FR) | 2026-05-15 | — | — | WO | disclosed |
| EP-4741375-A1 | SULFONYLUREA DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | Qubit Pharmaceuticals (FR) | 2026-05-13 | — | — | EP | disclosed |