Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 2/20 | 0.54 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38655263 | 0.85 | ERN1 (0.51) | ERN1MRGPRX4NPC1RAB9ACA12 | |
| SCHEMBL14892283 | 0.82 | CDK8 (0.61) | CDK8ERN1NEK1GABRG2GABRB3 | |
| SCHEMBL15577477 | 0.80 | CDK8 (0.60) | CDK8ERN1NEK1GABRG2GABRB3 | |
| SCHEMBL4257073 | 0.80 | CDK8 (0.59) | CDK8ERN1NEK1GABRG2GABRB3 | |
| SCHEMBL38657085 | 0.80 | SLC2A1 (0.46) | ERN1 | |
| SCHEMBL7829981 | 0.78 | ERN1 (0.58) | CDK8ERN1NEK1GABRG2GABRB3 | |
| SCHEMBL30790370 | 0.78 | ERN1 (0.58) | CDK8ERN1NEK1GABRG2GABRB3 | |
| SCHEMBL990912 | 0.78 | MAPK1 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL30821487 | 0.78 | MAPK1 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL67941 | 0.78 | CA12 (0.68) | CDK8ERN1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102082-A1 | ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | GIPR, MC2R, GRPR | CDK8 1946/4885ERN1 4297/4885NEK1 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.