Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890194 | 1.00 | IKBKB (0.43) | IKBKBCTSKSYKKCNH2BRD4 | |
| SCHEMBL2262129 | 0.93 | IKBKB (0.44) | IKBKBCTSKSYKKCNH2BRD4 | |
| SCHEMBL2259038 | 0.81 | KCNH2 (0.42) | KCNH2CCNA2CDK2CYP2C9 | |
| SCHEMBL2262225 | 0.81 | KCNH2 (0.55) | KCNH2CYP2C9 | |
| SCHEMBL2260938 | 0.81 | KCNH2 (0.44) | IKBKBCTSKKCNH2CYP2C9 | |
| SCHEMBL28410274 | 0.79 | GPR119 (0.48) | SYKKCNH2IRAK4CYP2C9NSD2 | |
| SCHEMBL2263072 | 0.79 | KCNH2 (0.45) | CTSKKCNH2CTSLCTSBCTSS | |
| SCHEMBL28414910 | 0.79 | KCNH2 (0.45) | CTSKKCNH2BRD4ATAD2CTSL | |
| SCHEMBL2261778 | 0.78 | KCNH2 (0.41) | IKBKBCTSKKCNH2CYP2C9 | |
| SCHEMBL2260485 | 0.78 | KCNH2 (0.52) | IKBKBKCNH2CCNA2CDK2MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010902-A | Carbonyl substituted pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2026-05-12 | — | — | CN | disclosed |